Use of nanosystems to improve the anticancer effects of curcumin

• Andrea M. Araya-Sibaja,
• Norma J. Salazar-López,
• Krissia Wilhelm Romero,
• José R. Vega-Baudrit,
• J. Abraham Domínguez-Avila,
• Carlos A. Velázquez Contreras,
• Ramón E. Robles-Zepeda,
• Mirtha Navarro-Hoyos and
• Gustavo A. González-Aguilar

Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78

• studies performed on human subjects. Data generated in vitro and in animals should complement the efficacy of a treatment and can be used to determine its mechanisms of action at cellular and molecular scales. However, there is no substitute for human-derived data. Figure 1 summarizes relevant data

The role of convolutional neural networks in scanning probe microscopy: a review

• Ido Azuri,
• Irit Rosenhek-Goldian,
• Neta Regev-Rudzki,
• Georg Fantner and
• Sidney R. Cohen

Beilstein J. Nanotechnol. 2021, 12, 878–901, doi:10.3762/bjnano.12.66

Physical constraints lead to parallel evolution of micro- and nanostructures of animal adhesive pads: a review

• Thies H. Büscher and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2021, 12, 725–743, doi:10.3762/bjnano.12.57

• micro- and nanoscales at different phylogenetic levels, focus on insects as the largest animal group on earth, and subsequently zoom into the attachment pads of the stick and leaf insects (Phasmatodea) to explore convergent evolution of attachment pads at even smaller scales. Since convergent events

• surface irregularities of certain length scales. The range of length scales to which the adaptation is possible depends on the stiffness of the film. Spatulae are able to adapt even to nanoscale roughness [240][241]. Thick films within the smooth pads of the bush cricket Tettigonia viridissima and the

Electromigration-induced formation of percolating adsorbate islands during condensation from the gaseous phase: a computational study

• Alina V. Dvornichenko,
• Vasyl O. Kharchenko and
• Dmitrii O. Kharchenko

Beilstein J. Nanotechnol. 2021, 12, 694–703, doi:10.3762/bjnano.12.55

• spatial instability [53][54][55][56][57][58]. The transient patterns realized during system evolution will disappear at large time scales leading to the homogeneous distribution of the coverage field [59]. In order to stabilize these transient patterns the reaction component R(x) can be generalized by

• of vertical motion of adatoms k∥, one can define domains of main system parameters, in which pattern formation is possible. In particular, for the case λ(κ) ≤ 0 κ any spatial instability that can be realized at the initial stages of the system evolution disappears at long time scales leading to a

• snapshots in Figure 3b). These islands diffuse and interact. At large time scales the dispersion attains a constant non-zero value and the surface layer is characterized by stationary surface patterns, that is, separated adsorbate islands on the substrate (top panel in Figure 3b) or separated holes inside

Colloidal particle aggregation: mechanism of assembly studied via constructal theory modeling

• Scott C. Bukosky,
• Sukrith Dev,
• Monica S. Allen and
• Jeffery W. Allen

Beilstein J. Nanotechnol. 2021, 12, 413–423, doi:10.3762/bjnano.12.33

• the magnitude of the DLVO force, which scales linearly with particle radius, that is, larger particles are more attractive/repulsive. Ultimately, only the solvent properties are responsible for determining whether or not aggregation will be favorable. Similar to varying the particle spacing

Determination of elastic moduli of elastic–plastic microspherical materials using nanoindentation simulation without mechanical polishing

• Hongzhou Li and
• Jialian Chen

Beilstein J. Nanotechnol. 2021, 12, 213–221, doi:10.3762/bjnano.12.17

• characterization of the mechanical behavior of filaments [1], thin films [2], microplastics, coatings, powders, small crystals, and other materials at small scales. One of the great advantages of the technique is that many mechanical properties of materials can be determined from the analysis of indentation load

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

Bulk chemical composition contrast from attractive forces in AFM force spectroscopy

• Dorothee Silbernagl,
• Media Ghasem Zadeh Khorasani,
• Natalia Cano Murillo,
• Anna Maria Elert and
• Heinz Sturm

Beilstein J. Nanotechnol. 2021, 12, 58–71, doi:10.3762/bjnano.12.5

• Fattr, a clear distinction can be made. Note that the measurements shown in Figure 3 were performed with a different AFM probe (tip B) than the measurements shown in Figure 2 (tip A). Hence, the different scales for the Fattr values. Model sample epoxy/polycarbonate Here, we consider a sample that was

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• HIM in the field of medicine came in 2011 when Bazou et al. used the HIM to study tumor cells [9][10] and Arey et al. studied the interaction of nanoparticles with alveolar epithelial cells [11]. In the following two years, reports on HIM imaging of the nanostructures on butterfly scales by Boden et

Fabrication of nano/microstructures for SERS substrates using an electrochemical method

• Jingran Zhang,
• Tianqi Jia,
• Xiaoping Li,
• Junjie Yang,
• Zhengkai Li,
• Guangfeng Shi,
• Xinming Zhang and
• Zuobin Wang

Beilstein J. Nanotechnol. 2020, 11, 1568–1576, doi:10.3762/bjnano.11.139

• ] fabricated micro/nanostructures on the surface of Au-coated single crystal silicon. By changing the etching time and current, micro/nanostructures with different size scales and geometric shapes (such as hexagons and pentagons) were obtained. Compared with other geometries, the hexagonal micro/nanostructure

Adsorption and self-assembly of porphyrins on ultrathin CoO films on Ir(100)

• Feifei Xiang,
• Tobias Schmitt,
• Marco Raschmann and
• M. Alexander Schneider

Beilstein J. Nanotechnol. 2020, 11, 1516–1524, doi:10.3762/bjnano.11.134

• assembly changed between (b) and (c). (a) 1 on 2BL CoO deposited at 200 K and imaged at 80 K. The molecules appear as round features unless close to a neighboring molecule or substrate defect. This indicates that 1 rotates around its central Co ion at time scales that are fast with respect to the STM

Helium ion microscope – secondary ion mass spectrometry for geological materials

• Matthew R. Ball,
• Richard J. M. Taylor,
• Joshua F. Einsle,
• Fouzia Khanom,
• Christelle Guillermier and
• Richard J. Harrison

Beilstein J. Nanotechnol. 2020, 11, 1504–1515, doi:10.3762/bjnano.11.133

• and 56Fe mass images after 20 min of rastered beam exposure on the sample; c) raw and processed 90Zr and 56Fe mass images after 240 min of rastered beam exposure on the sample. Initial maps were 512 × 512 pixels, covering a field of view of 70 µm. The scales show the absolute number of ions detected

Protruding hydrogen atoms as markers for the molecular orientation of a metallocene

• Linda Laflör,
• Michael Reichling and
• Philipp Rahe

Beilstein J. Nanotechnol. 2020, 11, 1432–1438, doi:10.3762/bjnano.11.127

• molecules are marked by a green dumbbell. (a) Experimental STM image (U = 4 V, It = 2 pA). (b–e) Experimental constant-height NC-AFM data (f0 = 24363 Hz, Q0 ≈ 6000, A0 = 0.27 nm). Frequency shift ranges are shown below each image (inverted colour scales are used). A four pixel averaging filter was applied

On the frequency dependence of viscoelastic material characterization with intermittent-contact dynamic atomic force microscopy: avoiding mischaracterization across large frequency ranges

• Enrique A. López-Guerra and
• Santiago D. Solares

Beilstein J. Nanotechnol. 2020, 11, 1409–1418, doi:10.3762/bjnano.11.125

• correspondence principle, was introduced by Efremov et al. [34], which they applied to living cells. In contrast to the discrete nature of the Generalized Maxwell model, which allows the use of arbitrary parameters at different time scales modeled by different spring–damper combinations, they focused primarily

• , Figure 4b again confirms the expectations, indicating that the difference in indentation between the two materials is smaller than at 70 kHz (notice that Figure 4a and Figure 4b have different horizontal scales). A calculation using Equation 2 indicates that the storage modulus for material 1

• principle possible to access short time scales (high frequencies) even with conventional experimental setups. However, this principle only applies to thermo-rheologically simple materials, such as certain types of simple polymers [16][18][45]. There may also emerge experimental complexities related to

Superconductor–insulator transition in capacitively coupled superconducting nanowires

• Alex Latyshev,
• Andrew G. Semenov and
• Andrei D. Zaikin

Beilstein J. Nanotechnol. 2020, 11, 1402–1408, doi:10.3762/bjnano.11.124

• standard procedure [29] and proceeding to bigger and bigger scales Λ, we eventually arrive at the following RG equations for the QPS fugacities y1 and y2: where λ11 and λ22 are diagonal elements of the matrix (Equation 15). Note that here we restrict our RG analysis to the lowest order in y1,2 which is

Analysis of catalyst surface wetting: the early stage of epitaxial germanium nanowire growth

• Owen C. Ernst,
• Felix Lange,
• David Uebel,
• Thomas Teubner and
• Torsten Boeck

Beilstein J. Nanotechnol. 2020, 11, 1371–1380, doi:10.3762/bjnano.11.121

• calculations. Hamaker constants correspond to the susceptibility of particles to an electric field of very small length scales generated by the particles themselves [28]. For this reason, these constants are used to determine energy and force values in van der Waals interactions. A more detailed description of

Atomic defect classification of the H–Si(100) surface through multi-mode scanning probe microscopy

• Jeremiah Croshaw,
• Thomas Dienel,
• Taleana Huff and
• Robert Wolkow

Beilstein J. Nanotechnol. 2020, 11, 1346–1360, doi:10.3762/bjnano.11.119

• , as indicated by the height scales in the constant current STM images in Figure 2k-1,2. In the constant height STM image of Figure 2k-3, it shows only a slight increase in conductivity localized to a single atomic site, suggesting that the Si atom on one side of the dimer is perhaps replaced by this

An atomic force microscope integrated with a helium ion microscope for correlative nanoscale characterization

• Santiago H. Andany,
• Gregor Hlawacek,
• Stefan Hummel,
• Charlène Brillard,
• Mustafa Kangül and
• Georg E. Fantner

Beilstein J. Nanotechnol. 2020, 11, 1272–1279, doi:10.3762/bjnano.11.111

• - and time-scales. Conclusion We have demonstrated the integration of an atomic force microscope into a helium ion microscope. Correlative measurements of AFM topography with He ion imaging and modification demonstrate the feasibility of this integration. The complementarity of the two methods in terms

Thermophoretic tweezers for single nanoparticle manipulation

• Jošt Stergar and
• Natan Osterman

Beilstein J. Nanotechnol. 2020, 11, 1126–1133, doi:10.3762/bjnano.11.97

• Nobel prize in 2018, seem like a perfect tool for such manipulations. Still, since the gradient force scales with the volume of the trapped object, only particles larger than about a few hundred nanometers in diameter can be easily trapped and manipulated in practice. A contrast in the index of

• easily compensated either by lowering the heating laser power (and consequently decreasing ∇T) or by increasing the feedback frequency, as the average distance the particle moves during one “kick” scales with ∝ST∇T/f. Figure 3c shows the dependence of the trap stiffness (calculated using Equation 1) on

• different length scales. First, the fine position of the particle inside the microscope field-of-view (FOV) can be achieved by trapping the particle and then moving the desired trap center. Larger movement exceeding the FOV can be easily reached by translating the sample mount in the microscope while the

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• also proved that different cells respond to hyperthermia treatment at different time scales [142]. However, there are in vivo hyperthermia experiments that showed that the best size range for SPION is between 15 and 50 nm, and that cubic nanoparticles have the highest surface absorption rate [143]. The

Wet-spinning of magneto-responsive helical chitosan microfibers

• Dorothea Brüggemann,
• Johanna Michel,
• Naiana Suter,
• Matheus Grande de Aguiar and
• Michael Maas

Beilstein J. Nanotechnol. 2020, 11, 991–999, doi:10.3762/bjnano.11.83

• Bremen - City University of Applied Sciences, Neustadtswall 30, 28199 Bremen, Germany Advanced Ceramics, University of Bremen, Am Biologischen Garten 2, 28359 Bremen, Germany 10.3762/bjnano.11.83 Abstract Helical structures can be found in nature at various length scales ranging from the molecular level

Extracting viscoelastic material parameters using an atomic force microscope and static force spectroscopy

• Cameron H. Parvini,
• M. A. S. R. Saadi and
• Santiago D. Solares

Beilstein J. Nanotechnol. 2020, 11, 922–937, doi:10.3762/bjnano.11.77

• due to a lack of resolution (for small time scales) or limitations on the experiment length (long time scales) these additional terms will introduce significant error in the parameters extracted. Furthermore if the parameter set obtained is extrapolated for new loading conditions, it will incorrectly

• response of the material at short timescales; the second is the characteristic time (τn), which scales the third parameter, the characteristic compliance (Jn), such that it contracts on a specific timescale corresponding to the n-th branch of the generalized Voigt model. By inserting Equation 7 into

• ; Fconv,wrap: Scales the output of subref by the time step dt, adds the glassy compliance term, and re-samples the result to logarithmic scaling. This is the function provided to lsqcurvefit(). Because lsqcurvefit() calculates the cost internally, it is not necessary to define a function for this purpose

Measurement of electrostatic tip–sample interactions by time-domain Kelvin probe force microscopy

• Christian Ritz,
• Tino Wagner and
• Andreas Stemmer

Beilstein J. Nanotechnol. 2020, 11, 911–921, doi:10.3762/bjnano.11.76

• effect is amplified when a significant change in the capacitance gradient is present. To reduce the impact of this component onto the height measurement, the modulation amplitude Uac must be minimized. Since the signal-to-noise ratio (SNR) scales with Uac, this is only possible to a certain extent

Light–matter interactions in two-dimensional layered WSe₂ for gauging evolution of phonon dynamics

• Avra S. Bandyopadhyay,
• Chandan Biswas and
• Anupama B. Kaul

Beilstein J. Nanotechnol. 2020, 11, 782–797, doi:10.3762/bjnano.11.63

• , calculated from the slope of the low-energy edge of the excitonic mode of the PL spectra. The theory of spectral line shape in the Raman spectrum predicts a Lorentzian distribution of a collected signal in a dispersive medium, where the full-width-half-maximum (FWHM) scales as 1/τ, and not surprisingly, τ is

Quantitative determination of the interaction potential between two surfaces using frequency-modulated atomic force microscopy

• Nicholas Chan,
• Carrie Lin,
• Tevis Jacobs,
• Robert W. Carpick and
• Philip Egberts

Beilstein J. Nanotechnol. 2020, 11, 729–739, doi:10.3762/bjnano.11.60

• such issues. For example, the adsorption of self-assembled monolayers on contacting surfaces is one method by which the surface can be modified to reduce the detrimental impacts of adhesion, friction and wear [15][16][17]. The nanometer length scales over which these processes modify surface

• pyrolytic graphite (HOPG) or a KBr crystal to negate the effects of varying scales of roughness, which [12] suggests should be a contributing factor. Qualitatively, there is a general mismatch in behavior when comparing the majority of experimental results with the LJ F(z) curves. In particular, the LJ F(z