Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione

• Barbara Pem,
• Igor M. Pongrac,
• Lea Ulm,
• Ivan Pavičić,
• Valerije Vrček,
• Darija Domazet Jurašin,
• Marija Ljubojević,
• Adela Krivohlavek and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175

• +). The comparison with data published on polymer-coated nanoparticles evidenced that surface modification with biothiols made them safer for the biological environment. In vitro evaluation on human cells demonstrated that the toxicity of AgNPs and AuNPs prepared in the presence of cysteine was similar to

• vivo assessment of NP toxicity on aquatic organisms evidenced that surface modification of metallic NPs with biothiols made them safer for the environment, while in vitro experiments on mammalian cells demonstrated that AgNPs and AuNPs functionalized with glutathione had a significant biological impact

• , the need emerges for the development of safe, surface-modified nanosystems. For the first time, safety profiling of AgNPs and AuNPs prepared by using cysteine and glutathione as stabilizing agents was performed. A careful and comprehensive evaluation of physico-chemical properties and surface

Scavenging of reactive oxygen species by phenolic compound-modified maghemite nanoparticles

• Małgorzata Świętek,
• Yi-Chin Lu,
• Rafał Konefał,
• Liliana P. Ferreira,
• M. Margarida Cruz,
• Yunn-Hwa Ma and
• Daniel Horák

Beilstein J. Nanotechnol. 2019, 10, 1073–1088, doi:10.3762/bjnano.10.108

• ), to yield γ-Fe2O3@Hep-CS-G, γ-Fe2O3@Hep-CS-H, and γ-Fe2O3@Hep-CS-P particles, respectively. Surface modification of the particles was analyzed by transmission electron microscopy, dynamic light scattering, attenuated total reflection Fourier transform infrared spectroscopy, and thermogravimetric

• method chosen to attach phenolic compounds on the chitosan rather than by the phenolic compounds themselves. Moreover, the chitosans with low molecular weight were highly soluble in 2 wt % acetic acid; they could also be dissolved in water, which is important for surface modification of the magnetic

• , such as pigs and cattle [28]. Unfractionated and low-molecular-weight heparins are used in medicine as indirect anticoagulants for thrombosis prevention and treatment [29]. The presence of sulfate and carboxyl groups in heparin was critical for surface modification of the positively charged γ-Fe2O3

Ultrathin hydrophobic films based on the metal organic framework UiO-66-COOH(Zr)

• Miguel A. Andrés,
• Clemence Sicard,
• Christian Serre,
• Olivier Roubeau and
• Ignacio Gascón

Beilstein J. Nanotechnol. 2019, 10, 654–665, doi:10.3762/bjnano.10.65

• . Keywords: hydrophobic coating; Langmuir–Blodgett (LB) films; metal organic framework (MOF); surface modification; UiO-66-COOH(Zr); Introduction Metal organic frameworks (MOFs) are well-known, crystalline, porous materials formed by metal ions (or metallic clusters) and organic ligands coordinated in a pre

Hydrophilicity and carbon chain length effects on the gas sensing properties of chemoresistive, self-assembled monolayer carbon nanotube sensors

• Juan Casanova-Cháfer,
• Carla Bittencourt and
• Eduard Llobet

Beilstein J. Nanotechnol. 2019, 10, 565–577, doi:10.3762/bjnano.10.58

• length of these carbon nanotubes is 1.5 µm and the average diameter is 9.5 nm. The surface of the carbon nanotubes was modified with –COOH groups, with a value of mass greater than 8%. This surface modification was performed by Nanocyl S.A. via an oxygen-plasma treatment. An attempt to decorate pristine

Direct observation of the CVD growth of monolayer MoS₂ using in situ optical spectroscopy

• Claudia Beatriz López-Posadas,
• Yaxu Wei,
• Wanfu Shen,
• Daniel Kahr,
• Michael Hohage and
• Lidong Sun

Beilstein J. Nanotechnol. 2019, 10, 557–564, doi:10.3762/bjnano.10.57

• reflectance spectroscopy (DRS), which measures the normalized difference between the reflectance of the bare surface and the surface covered by thin films, possesses an enhanced sensitivity to the surface modification and ultrathin film growth [25][26]. This technique has been successfully applied to reveal

One-step nonhydrolytic sol–gel synthesis of mesoporous TiO₂ phosphonate hybrid materials

• Yanhui Wang,
• P. Hubert Mutin and
• Johan G. Alauzun

Beilstein J. Nanotechnol. 2019, 10, 356–362, doi:10.3762/bjnano.10.35

• hybrids are obtained in two steps, by surface modification of a porous metal oxide support [17][18][19]. Nonhydrolytic (or nonaqueous) sol–gel (NHSG) chemistry has provided simple and powerful routes to synthesize oxides or mixed oxides with different morphologies (e.g., nanoparticles) or textures (e.g

• the 10 to 35 ppm range. Similar broad resonances have been reported for TiO2–phenylphosphonate hybrid materials prepared in a two-step sol–gel process from Ti(OiPr)4 and PhPO3H2 [15], whereas the hybrid materials obtained by surface modification of anatase supports usually show narrower resonances [36

Wet chemistry route for the decoration of carbon nanotubes with iron oxide nanoparticles for gas sensing

• Hussam M. Elnabawy,
• Juan Casanova-Chafer,
• Badawi Anis,
• Mostafa Fedawy,
• Mattia Scardamaglia,
• Carla Bittencourt,
• Ahmed S. G. Khalil,
• Eduard Llobet and
• Xavier Vilanova

Beilstein J. Nanotechnol. 2019, 10, 105–118, doi:10.3762/bjnano.10.10

• with iron oxide nanoparticles substantially ameliorated the response towards nitrogen dioxide. Keywords: benzene detection; doping; gas sensor; metal nanoparticle decoration; multiwalled carbon nanotubes; NO2 detection; room temperature gas sensing; surface modification; Introduction Carbon nanotubes

Femtosecond laser-assisted fabrication of chalcopyrite micro-concentrator photovoltaics

• Franziska Ringleb,
• Stefan Andree,
• Berit Heidmann,
• Jörn Bonse,
• Katharina Eylers,
• Owen Ernst,
• Torsten Boeck,
• Martina Schmid and
• Jörg Krüger

Beilstein J. Nanotechnol. 2018, 9, 3025–3038, doi:10.3762/bjnano.9.281

• array. The series of spots at the surface illustrates, that a stronger surface modification or even the formation of a crater can be achieved by increasing the number of laser pulses per spot as well as by increasing the laser fluence (energy density). Selected scanning electron microscopy (SEM) images

Colloidal chemistry with patchy silica nanoparticles

• Pierre-Etienne Rouet,
• Cyril Chomette,
• Laurent Adumeau,
• Etienne Duguet and
• Serge Ravaine

Beilstein J. Nanotechnol. 2018, 9, 2989–2998, doi:10.3762/bjnano.9.278

• nanoparticles and the chemical composition of the spherical satellites, we demonstrate that a vast collection of CMs are accessible through assemblies that are analogous to chemical reactions (Figure 1). Results and Discussion Synthesis and surface modification of the precursors The first type of precursors

• . Butyl chloromethyl ether was synthesized according to a recipe already published [27]. Synthesis and surface modification of the spherical satellites Synthesis of the “pre-seeds” In a similar manner as described in [28], 100 mL of L-arginine aqueous solution (6 mM) were added into a 150 mL vial

• by the citrate-reduction method reported by Turkevich [29]. SiO2 coating was carried out after surface functionalization of the gold nanoparticles by using a PEG-SH (Mw = 5000) aqueous solution in a similar manner as described in [23]. The surface modification allowed for the replacement of the

Co-intercalated layered double hydroxides as thermal and photo-oxidation stabilizers for polypropylene

• Qian Zhang,
• Qiyu Gu,
• Fabrice Leroux,
• Pinggui Tang,
• Dianqing Li and
• Yongjun Feng

Beilstein J. Nanotechnol. 2018, 9, 2980–2988, doi:10.3762/bjnano.9.277

• further washed twice with acetone with surface modification and then was used for the preparation of H1M1-Ca2Al/PP composites. To obtain the H1M1-Ca2Al powder, part of the slurry was dried in an oven at 80 °C for 24 h. Co-intercalated HnMn′-Ca2Al with different molar ratios and MP-Ca2Al were obtained

Layered calcium phenylphosphonate: a hybrid material for a new generation of nanofillers

• Kateřina Kopecká,
• Ludvík Beneš,
• Klára Melánová,
• Vítězslav Zima,
• Petr Knotek and
• Kateřina Zetková

Beilstein J. Nanotechnol. 2018, 9, 2906–2915, doi:10.3762/bjnano.9.269

• structure or by a surface modification [3][4] by grafting organophilic functional groups onto the clay surface, leading to the synthesis of hybrid organic–inorganic materials [5]. Layered metal organophosphonates are a class of materials which exhibit a hybrid character by their nature. They are generally

Controlling surface morphology and sensitivity of granular and porous silver films for surface-enhanced Raman scattering, SERS

• Sherif Okeil and
• Jörg J. Schneider

Beilstein J. Nanotechnol. 2018, 9, 2813–2831, doi:10.3762/bjnano.9.263

• ][60]. Recently, other methods emerged with the aim of producing SERS substrates at low cost, enabling their large-scale production. These methods include inkjet-printing and pen-on-paper approaches [61][62]. Plasma treatment has been widely used for the last decades for microelectronics and surface

• modification in industry [63][64]. A large variety of plasmas exist depending on the excitation source, the operating pressure and the device geometry [63][65]. Advantages of the use of a radio frequency (rf) plasma for chemical modification is that no hazardous chemicals and solvents are involved. Moreover

Biomimetic surface structures in steel fabricated with femtosecond laser pulses: influence of laser rescanning on morphology and wettability

• Camilo Florian Baron,
• Alexandros Mimidis,
• Daniel Puerto,
• Evangelos Skoulas,
• Emmanuel Stratakis,
• Javier Solis and
• Jan Siegel

Beilstein J. Nanotechnol. 2018, 9, 2802–2812, doi:10.3762/bjnano.9.262

• influences the surface energy and thus the wetting behavior [5][6][7][8][9][10]. A particular kind of controllable surface modification induced by pulsed lasers was discovered in 1965 by Milton Birnbaum [11] – upon irradiation of a germanium wafer with multiple laser pulses, self-organized periodic surface

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe₂O₃ nanoparticles towards human tumor cells

• Zdeněk Plichta,
• Yulia Kozak,
• Rostyslav Panchuk,
• Viktoria Sokolova,
• Matthias Epple,
• Lesya Kobylinska,
• Pavla Jendelová and
• Daniel Horák

Beilstein J. Nanotechnol. 2018, 9, 2533–2545, doi:10.3762/bjnano.9.236

• relatively high values of Dh. The ζ-potential of the particles amounted to −35 mV (pH 7.3), which is sufficient for short-term colloidal stability of the particles. Coating of γ-Fe2O3 nanoparticles with poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) Surface modification of nanoparticles is a general

Preparation of micro/nanopatterned gelatins crosslinked with genipin for biocompatible dental implants

• Reika Makita,
• Tsukasa Akasaka,
• Seiichi Tamagawa,
• Yasuhiro Yoshida,
• Saori Miyata,
• Hirofumi Miyaji and
• Tsutomu Sugaya

Beilstein J. Nanotechnol. 2018, 9, 1735–1754, doi:10.3762/bjnano.9.165

• surfaces using genipin crosslinking, with the aim of understanding the use of patterning in surface modification of dental implants. Results: Grooves, holes, and pillars, with widths or diameters of 2 µm, 1 µm, or 500 nm were fabricated using a combination of molding and genipin crosslinking of gelatin

• . Following this, cell attachment and proliferation on the resulting gelatin surface patterns were assessed using human osteoblastic Saos-2 cells, with the aim of understanding the use of these gelatin patterned surfaces in surface modification of dental implants. Cell attachment increased as a result of

Cr(VI) remediation from aqueous environment through modified-TiO₂-mediated photocatalytic reduction

• Rashmi Acharya,
• Brundabana Naik and
• Kulamani Parida

Beilstein J. Nanotechnol. 2018, 9, 1448–1470, doi:10.3762/bjnano.9.137

Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• nanoparticles have a shorter biological half-life and are cleared by the reticuloendothelial system [32]. For biomedical purposes, SPIOs must be biocompatible, colloidally stable, and well-dispersed in physiological buffers, which is often accomplished by surface modification of the magnetic nanoparticles with

• capable of initiating a strong electrostatic repulsion between the nanoparticles and the negatively charged waveguide. However, unlike PEG-SPIOs, uncoated SPIOs likely stuck to the waveguide owning to the absence of surface modification. Without a surface coating, which acts like a lubricant or spring

Noble metal-modified titania with visible-light activity for the decomposition of microorganisms

• Maya Endo,
• Zhishun Wei,
• Kunlei Wang,
• Baris Karabiyik,
• Kenta Yoshiiri,
• Paulina Rokicka,
• Bunsho Ohtani,
• Agata Markowska-Szczupak and
• Ewa Kowalska

Beilstein J. Nanotechnol. 2018, 9, 829–841, doi:10.3762/bjnano.9.77

• , by morphology design [22][23][24][25][26], surface modification [27][28][29][30][31][32], doping [33][34][35][36], or the formation of heterojunctions with other semiconductors [37][38][39][40]. Modification with noble metals seems the most promising as it is well known that under UV irradiation

Surface-plasmon-enhanced ultraviolet emission of Au-decorated ZnO structures for gas sensing and photocatalytic devices

• T. Anh Thu Do,
• Truong Giang Ho,
• Thu Hoai Bui,
• Quang Ngan Pham,
• Hong Thai Giang,
• Thi Thu Do,
• Duc Van Nguyen and
• Dai Lam Tran

Beilstein J. Nanotechnol. 2018, 9, 771–779, doi:10.3762/bjnano.9.70

• factors, including absorbed oxygen species (O2−, O−, and O2−), charge carrier concentration, and the defects and vacancies on the ZnO surfaces. The gas response performance can be improved by a charge transfer process through surface modification [3][5][6] and doping of catalytic materials [7][8][9]. The

Heavy-metal detectors based on modified ferrite nanoparticles

• Urszula Klekotka,
• Ewelina Wińska,
• Elżbieta Zambrzycka-Szelewa,
• Dariusz Satuła and
• Beata Kalska-Szostko

Beilstein J. Nanotechnol. 2018, 9, 762–770, doi:10.3762/bjnano.9.69

• composition and surface modification. The aim of the study is to examine the efficiency of adsorption of heavy metals in artificial solutions on doped magnetite nanoparticles (Ca, Co, Mn, Ni) surface-modified with PA, SA, AA, 3-PPA or 16-PHDA linkers. Experimental Reagents and solutions Chemicals used in this

• surface modification. The obtained images for each kind of fabricated ferrites are presented in Figure 2. The TEM images show that regardless of doping (Ca2+, Co2+, Mn2+ or Ni2+), the studied nanoparticles exhibit a similar round shape and average size. In Table 1, diameters of every type of synthesized

• [15]. Therefore, the origin of these signals is most probable due to heavy ion adsorption. However, due to a lack of reference information, it is the only speculation on the origin of appearing new signals. Raman spectroscopy After every step (synthesis, surface modification, and heavy metal

Single-step process to improve the mechanical properties of carbon nanotube yarn

• Maria Cecilia Evora,
• Xinyi Lu,
• Nitilaksha Hiremath,
• Nam-Goo Kang,
• Kunlun Hong,
• Roberto Uribe,
• Gajanan Bhat and
• Jimmy Mays

Beilstein J. Nanotechnol. 2018, 9, 545–554, doi:10.3762/bjnano.9.52

• single-step surface modification of CNTs to improve the mechanical properties of this material. To this end, CNT yarns were simultaneously functionalized and crosslinked using acrylic acid (AA) and acrylonitrile (AN) in an e-beam irradiation process. The chemical modification of CNT yarns was confirmed

Wafer-scale bioactive substrate patterning by chemical lift-off lithography

• Chong-You Chen,
• Chang-Ming Wang,
• Hsiang-Hua Li,
• Hong-Hseng Chan and
• Wei-Ssu Liao

Beilstein J. Nanotechnol. 2018, 9, 311–320, doi:10.3762/bjnano.9.31

• -arrangement of silane or thiol molecules on silica or Au surfaces, which has been proven as a convenient route for the fabrication of functional surfaces toward versatile targets [12][13][14][15][16]. In addition to direct surface modification, the versatility of anchoring molecule tail groups provides

BN/Ag hybrid nanomaterials with petal-like surfaces as catalysts and antibacterial agents

• Konstantin L. Firestein,
• Denis V. Leybo,
• Alexander E. Steinman,
• Andrey M. Kovalskii,
• Andrei T. Matveev,
• Anton M. Manakhov,
• Irina V. Sukhorukova,
• Pavel V. Slukin,
• Nadezda K. Fursova,
• Sergey G. Ignatov,
• Dmitri V. Golberg and
• Dmitry V. Shtansky

Beilstein J. Nanotechnol. 2018, 9, 250–261, doi:10.3762/bjnano.9.27

• nanostructures opens up new opportunities to improve the performance of hybrid nanomaterials. Many techniques for surface modification [4] and band-gap engineering [41][42] were described in the past few years. This allows for a control of size and homogeneity of Ag NPs, adhesion and charge distribution on the

Refractive index sensing and surface-enhanced Raman spectroscopy using silver–gold layered bimetallic plasmonic crystals

• Somi Kang,
• Sean E. Lehman,
• Matthew V. Schulmerich,
• An-Phong Le,
• Tae-woo Lee,
• Stephen K. Gray,
• Rohit Bhargava and
• Ralph G. Nuzzo

Beilstein J. Nanotechnol. 2017, 8, 2492–2503, doi:10.3762/bjnano.8.249

• [40][41][42]. It is Au, however, that is more widely utilized for analytical applications due to its long-term environmental stability, ease of surface modification, and biocompatibility [43]. The present study explores means for realizing synergy in utilizing the complementary attributes of each

Photobleaching of YOYO-1 in super-resolution single DNA fluorescence imaging

• Joseph R. Pyle and
• Jixin Chen

Beilstein J. Nanotechnol. 2017, 8, 2296–2306, doi:10.3762/bjnano.8.229

• , immobilize, and image a single DNA using the established protocol and our fluorescence microscope. Glass cover slip substrates modified with amino silane are used to immobilize single DNA molecules (Figure 3). After surface modification, the water contact angle for the cover slips is 48 ± 4° which is

• -localized molecules in each frame. Scheme and image of the optical microscope. (a) Scheme of glass surface modification and DNA immobilization. (b) Fluorescent image of stretched DNA molecules on the substrate that have been labeled with YOYO-1. The inset shows a droplet of water on the substrate before DNA