Self-assembly of a terbium(III) 1D coordination polymer on mica

• Quentin Evrard,
• Giuseppe Cucinotta,
• Felix Houard,
• Guillaume Calvez,
• Yan Suffren,
• Carole Daiguebonne,
• Olivier Guillou,
• Andrea Caneschi,
• Matteo Mannini and
• Kevin Bernot

Beilstein J. Nanotechnol. 2019, 10, 2440–2448, doi:10.3762/bjnano.10.234

• quenching [30] and by the decrease of the lifetime from 375 µs for [Tb(hfac)3·2H2O] to 132 µs for [Tb(hfac)3·2H2O]n@mica (Table 1). Furthermore, the very small amount of luminescent material present on the mica substrate reduces the luminescence intensity (see magnetic quantification). The quantum yields

Nonlinear absorption and scattering of a single plasmonic nanostructure characterized by x-scan technique

• Tushar C. Jagadale,
• Dhanya S. Murali and
• Shi-Wei Chu

Beilstein J. Nanotechnol. 2019, 10, 2182–2191, doi:10.3762/bjnano.10.211

• simultaneous quantification for the nonlinear behavior of scattering, absorption and total attenuation by a single nanostructure. At low excitation intensities, both scattering and absorption responses are linear, thus confirming the linearity of the detection system. At high excitation intensities, we found

Use of data processing for rapid detection of the prostate-specific antigen biomarker using immunomagnetic sandwich-type sensors

• Camila A. Proença,
• Tayane A. Freitas,
• Thaísa A. Baldo,
• Elsa M. Materón,
• Flávio M. Shimizu,
• Gabriella R. Ferreira,
• Frederico L. F. Soares,
• Ronaldo C. Faria and
• Osvaldo N. Oliveira Jr.

Beilstein J. Nanotechnol. 2019, 10, 2171–2181, doi:10.3762/bjnano.10.210

• quantification with the immunosensor is lower than the threshold established for the serum level found in patients with prostate cancer (above 3.6 ng·mL−1 stage A1) [56]. The samples were diluted in PBS for reaching the linear range, providing a response within the stipulated standards for the samples. Using the

• performed in a microfluidic system with a flow rate of 100 µL·min−1. The complex was injected with a syringe and the flow was stopped for 30 min. In the amperometric detection step, the biomarker quantification was performed by an indirect method through the electrochemical response of the marker in the

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

• Sebastian Pieper,
• Hannah Onafuye,
• Dennis Mulac,
• Jindrich Cinatl Jr.,
• Mark N. Wass,
• Martin Michaelis and
• Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 2062–2072, doi:10.3762/bjnano.10.201

• pictures were received at an accelerating voltage of 10,000 V and a working distance of 10 mm (CamScan CS4, Cambridge Scanning Company, Cambridge, UK). Doxorubicin quantification via HPLC-UV The amount of doxorubicin that had been incorporated into the nanoparticles was determined by HPLC-UV (HPLC 1200

Synthesis of highly active ETS-10-based titanosilicate for heterogeneously catalyzed transesterification of triglycerides

• Muhammad A. Zaheer,
• David Poppitz,
• Khavar Feyzullayeva,
• Marianne Wenzel,
• Jörg Matysik,
• Radomir Ljupkovic,
• Aleksandra Zarubica,
• Alexander A. Karavaev,
• Andreas Pöppl,
• Roger Gläser and
• Muslim Dvoyashkin

Beilstein J. Nanotechnol. 2019, 10, 2039–2061, doi:10.3762/bjnano.10.200

• ETS-4, AM-1 and quartz were detected (see also SEM data in Figure 3). The corresponding reflections at angles of 2θ are seen at, for example, 29.9° and 7.6° from ETS-4, 35.6° and 49.2° from AM-1, and 13.1° and 30.4° from quartz. The quantification of the presence of each phase in the prepared batch

Gold-coated plant virus as computed tomography imaging contrast agent

• Alaa A. A. Aljabali,
• Mazhar S. Al Zoubi,
• Khalid M. Al-Batanyeh,
• Ali Al-Radaideh,
• Mohammad A. Obeid,
• Abeer Al Sharabi,
• Walhan Alshaer,
• Bayan AbuFares,
• Tasnim Al-Zanati,
• Murtaza M. Tambuwala,
• Naveed Akbar and
• David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

• . Quantification of the amount of antibody attached to the VCAM1-PEG5000Au-CPMV was determined spectrophotometrically at λ = 565 nm using BCA reagent and found to be 1.95 ± 0.18 mg/mL gold. Further, the hydrodynamic radius of the VCAM1-PEG5000Au-CPMV increases from 50.2 ± 3.2 nm to 56.1 ± 2.4 nm after rigorous

• negative control following the same procedure. Antibody quantification Bicinchoninic acid (BCA) protein assay kit from ThermoFisher Scientific was used according to the manufacturer’s instructions [49]. VCAM1-PEG5000Au-CPMV and IgG-PEG5000Au-CPMV (200 μL of 0.1 mg Au) and BCA reagent (200 μL) were mixed

Long-term entrapment and temperature-controlled-release of SF₆ gas in metal–organic frameworks (MOFs)

• Hana Bunzen,
• Andreas Kalytta-Mewes,
• Leo van Wüllen and
• Dirk Volkmer

Beilstein J. Nanotechnol. 2019, 10, 1851–1859, doi:10.3762/bjnano.10.180

• phase by mass spectrometry (Figure S12 in Supporting Information File 1). As expected, upon adding the acid to the reaction vessel, the framework decomposed and an immediate evolution of gas bubbles was observed. The SF6 release could be followed by mass spectrometry; however, a precise quantification

Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione

• Barbara Pem,
• Igor M. Pongrac,
• Lea Ulm,
• Ivan Pavičić,
• Valerije Vrček,
• Darija Domazet Jurašin,
• Marija Ljubojević,
• Adela Krivohlavek and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175

• ). The dissolution behavior of AuNPs and AgNPs was tested by ultrafiltration followed by quantification of released free gold or silver ions. The test media were UPW, cell culture medium EMEM with the addition of 10% FBS, and standard culture media for Daphnia magna cultivation (SCM). Freshly prepared

• [87]. The reflection contrast mode of CLSM, as excellent non-invasive imaging strategy for label-free real-time tracking and quantification of non-fluorescent NPs [88], was used to visualize cellular uptake of NPs. In brief, the cells were grown in a 12-well chamber with glass slides (Eppendorf

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

• Elisabetta Esposito,
• Maddalena Sguizzato,
• Markus Drechsler,
• Paolo Mariani,
• Federica Carducci,
• Claudio Nastruzzi,
• Giuseppe Valacchi and
• Rita Cortesi

Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

• spectrophotometric quantification of the LDH released in culture medium, using a commercial kit (Sigma-Aldrich, Merck, Darmstadt, Germany), as previously described [43]. Human skin explant (HSE) culture Skin explants were prepared from the superfluous skin of healthy adult donors (18–60 years old). Breast or

Biocatalytic oligomerization-induced self-assembly of crystalline cellulose oligomers into nanoribbon networks assisted by organic solvents

• Yuuki Hata,
• Yuka Fukaya,
• Toshiki Sawada,
• Masahito Nishiura and
• Takeshi Serizawa

Beilstein J. Nanotechnol. 2019, 10, 1778–1788, doi:10.3762/bjnano.10.173

• centrifugation (20,400g)/redispersion cycles to remove more than 99.999% of the soluble fraction of the reaction mixtures. For MALDI–TOF mass spectrometry, the purified product dispersions were stored at 4 °C until use. For the quantification of the insoluble products, a volume of the purified product

Synthesis of nickel/gallium nanoalloys using a dual-source approach in 1-alkyl-3-methylimidazole ionic liquids

• Ilka Simon,
• Julius Hornung,
• Juri Barthel,
• Jörg Thomas,
• Maik Finze,
• Roland A. Fischer and
• Christoph Janiak

Beilstein J. Nanotechnol. 2019, 10, 1754–1767, doi:10.3762/bjnano.10.171

• selected-area energy diffraction (SAED) are required. Presumably, due to the small size of the nanoparticles, these measurements yielded no diffractograms. Therefore, the nanoparticles can only be described as non-crystalline or amorphous. Quantification of EDX spectra from three different spots on the TEM

• size distribution of 2.5 ± 0.5 nm ([BMIm][BF4], Supporting Information File 1, Figure S2 and Figure S3) and 5 ± 1 nm (PC, Supporting Information File 1, Figure S4). EDX quantification over different spots on the TEM grid also shows equimolar ratios of nickel to gallium (Supporting Information File 1

• the microwave reactor. Subsequently, the TEM images show spherical and crystalline nanoparticles with a small size distribution of 5 ± 1 nm (Figure 3). Through the increased decomposition time the particles were grown slightly larger. The metal composition quantification by EDX spectra from three

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

• Hannah Onafuye,
• Sebastian Pieper,
• Dennis Mulac,
• Jindrich Cinatl Jr.,
• Mark N. Wass,
• Klaus Langer and
• Martin Michaelis

Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

• , United Kingdom) and the sample was visualised with an accelerating voltage of 10 kV, a working distance of 10 mm, and 10,000-fold magnification. Doxorubicin quantification via HPLC-UV The amount of doxorubicin that was incorporated into the nanoparticles was determined by HPLC-UV (HPLC 1200 series

Tuning the performance of vanadium redox flow batteries by modifying the structural defects of the carbon felt electrode

• Ditty Dixon,
• Deepu Joseph Babu,
• Aiswarya Bhaskar,
• Hans-Michael Bruns,
• Joerg J. Schneider,
• Frieder Scheiba and
• Helmut Ehrenberg

Beilstein J. Nanotechnol. 2019, 10, 1698–1706, doi:10.3762/bjnano.10.165

• ) analysis of the samples was carried out. The N2-plasma-treated sample was characterized by a N 1s peak with maxima around 399 eV. The N 1s peak could be deconvoluted into pyridinic and pyrrolic N contributions, with maxima at 398.3 and 399.8 eV, respectively. The XPS results, as well as the quantification

• Voigt profiles (binding energy (BE) uncertainty: ±0.2 eV). The analyzer transmission function, Scofield sensitivity factors [29], and effective attenuation lengths (EALs) for photoelectrons were applied for quantification. The EALs were calculated using the standard TPP-2M formalism [30]. All spectra

Nanoscale spatial mapping of mechanical properties through dynamic atomic force microscopy

• Zahra Abooalizadeh,
• Leszek Josef Sudak and
• Philip Egberts

Beilstein J. Nanotechnol. 2019, 10, 1332–1347, doi:10.3762/bjnano.10.132

• excluded as a contributing factor to elastic modulus maps produced using dynamic AFM. CR-AFM showed a larger variation in amplitude over the step edges compared with FMM AFM. The quantification of the elastic modulus on the HOPG terrace was performed using FMM AFM and through analysis of the dynamics of

Tailoring the magnetic properties of cobalt ferrite nanoparticles using the polyol process

• Malek Bibani,
• Romain Breitwieser,
• Alex Aubert,
• Vincent Loyau,
• Silvana Mercone,
• Souad Ammar and
• Fayna Mammeri

Beilstein J. Nanotechnol. 2019, 10, 1166–1176, doi:10.3762/bjnano.10.116

• chemical analysis of the particles was checked by XRF, using a Panalytical MINIPAL4 X-ray fluorescence spectrometer, equipped with a rhodium X-ray tube operating at 30 kV and 87 μA current emission. Quantification was determined from pre-plotted calibration curves using standard Co and Fe solutions

Synthesis and characterization of quaternary La(Sr)S–TaS₂ misfit-layered nanotubes

• Marco Serra,
• Erumpukuthickal Ashokkumar Anumol,
• Dalit Stolovas,
• Iddo Pinkas,
• Ernesto Joselevich,
• Reshef Tenne,
• Andrey Enyashin and
• Francis Leonard Deepak

Beilstein J. Nanotechnol. 2019, 10, 1112–1124, doi:10.3762/bjnano.10.111

• spectroscopy (EDX) was performed using a SuperX EDX detector attached to this microscope using Bruker Esprit software. The quantification was done using the Cliff–Lorimer method. The samples for electron microscopy were prepared by dispersing the synthesized powder in ethyl alcohol, followed by ultrasonication

• left). The brighter walls and the darker hollow region are typical of a tubular morphology. The compositional map obtained from the nanotube (Figure 3 (top right)) shows that Sr is uniformly distributed in the nanotube. Elemental quantification from the EDX spectra indicates that 7–11 atom % of Sr

• substitution (93–89 atom % La) is achieved in a nanotube. The overlap of the L and Cu K lines for Ta might induce some error in quantification in the case of Ta. Also, due to the overlap of the L line for Sr and the M line for Ta, the weak Sr K line is used for mapping and quantification of Sr. Nanotubes with

CuInSe₂ quantum dots grown by molecular beam epitaxy on amorphous SiO₂ surfaces

• Henrique Limborço,
• Pedro M.P. Salomé,
• Rodrigo Ribeiro-Andrade,
• Jennifer P. Teixeira,
• Nicoleta Nicoara,
• Kamal Abderrafi,
• Joaquim P. Leitão,
• Juan C. Gonzalez and
• Sascha Sadewasser

Beilstein J. Nanotechnol. 2019, 10, 1103–1111, doi:10.3762/bjnano.10.110

• maps of that area for Se, Cu, In, Si, and O. The EDS mapping confirms that the nanodots are grown on top of a SiO2 layer, as shown by the presence of an oxygen-containing layer between the dots and the Si substrate. An EDS quantification performed in this nanodot (and several others) confirmed the

Glucose-derived carbon materials with tailored properties as electrocatalysts for the oxygen reduction reaction

• Rafael Gomes Morais,
• Natalia Rey-Raap,
• José Luís Figueiredo and
• Manuel Fernando Ribeiro Pereira

Beilstein J. Nanotechnol. 2019, 10, 1089–1102, doi:10.3762/bjnano.10.109

• analysis, a calibration of the CO and CO2 content was carried out, allowing the quantification of the TPD profiles. Electrochemical characterization The electrochemical measurements were performed on a PGSTAT 302N potentiostat/galvanostat by using a three-electrode cell configuration. Ag/AgCl (KCl 3 M) and

Enhanced inhibition of influenza virus infection by peptide–noble-metal nanoparticle conjugates

• Zaid K. Alghrair,
• David G. Fernig and
• Bahram Ebrahimi

Beilstein J. Nanotechnol. 2019, 10, 1038–1047, doi:10.3762/bjnano.10.104

• nanoparticles were synthesised with a range of molar fractions of FluPep ligand. After application of the gold nanoparticles to the column, the non-functionalised gold nanoparticles were collected in the flow-through and the functionalised ones were then eluted. Quantification of the gold nanoparticles by UV

• . Chromatography on CM-Sepharose was carried out with gold nanoparticles functionalised with different molar fractions of FluPep ligand. Top: images of columns after loading and washing with PBS. Bottom: quantification by absorption at 450 nm [18] of unbound (flow-through and PBS wash fractions) and bound (eluted

• cation-exchange chromatography. Silver nanoparticles functionalised with different molar fractions of FluPep ligand were subjected to chromatography on CM-Sepharose. Top: images of columns after loading and washing with PBS. Bottom: quantification of unbound (flow-through and PBS wash fractions) and

Correlation of surface-enhanced Raman scattering (SERS) with the surface density of gold nanoparticles: evaluation of the critical number of SERS tags for a detectable signal

• Vincenzo Amendola

Beilstein J. Nanotechnol. 2019, 10, 1016–1023, doi:10.3762/bjnano.10.102

• the absence of blinking or bleaching, and the possibility to excite in the red or near infrared spectral range, where most matrixes and substrates have low fluorescence background [13][17]. Therefore, due to the increasing demand for ultrasensitive identification and quantification of specific

• Scientec Vector calorimeter). The Raman signal was collected on an internal silicon chip which could account for small (less than 5%) intensity fluctuations of the Raman spectrometer and allowed for quantification of the noise intensity in the two measurement conditions. The acquisition time was fixed at

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

• Katrin Partikel,
• Robin Korte,
• Dennis Mulac,
• Hans-Ulrich Humpf and
• Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 1002–1015, doi:10.3762/bjnano.10.101

• concentrations above 75% (v/v) [8]. Nonetheless, the most intriguing observation of the present study is that the qualitative composition of the protein corona changed considerably with increasing human serum concentration in contrast to the incubation with FBS (Figure 3) even though the quantification of total

• depending on the serum concentration. The quantification of corona proteins was performed by Bradford assay and revealed a significant higher protein content after incubation with human serum (Figure 2). Nevertheless, this result did not only reflect the higher total concentration of proteins in pure human

• Millipore, Darmstadt, Germany). The elution was performed with pure acetonitrile as mobile phase at a constant flow rate of 1 mL/min and Lumogen® Red was detected using a fluorescence detector at an excitation wavelength of 575 nm and an emission wavelength of 610 nm. Quantification was carried out using a

Effects of gold and PCL- or PLLA-coated silica nanoparticles on brain endothelial cells and the blood–brain barrier

• Aniela Bittner,
• Angélique D. Ducray,
• Hans Rudolf Widmer,
• Michael H. Stoffel and
• Meike Mevissen

Beilstein J. Nanotechnol. 2019, 10, 941–954, doi:10.3762/bjnano.10.95

• quantitatively with high-content analysis using a fully automated inverted epifluorescence microscope (Figure 3E). As Au-NPs were only taken up to a very low extent, quantification was not carried out for these. PCL- and PLLA-NP uptake was measured after 0.5, 2 and 24 h of exposure to a concentration of [24.9 µg

• incubated with the respective primary antibody overnight at 4 °C on a shaker (Table 1). Following, the membranes were washed four times, incubated with the corresponding secondary antibody for 2 h at room temperature, and washed again. Quantification was carried out with ImageJ by measuring the intensity of

• of Akt or NF-κB (A, C). PCL- and PLLA-NPs led to decreased levels of P-MAPK, whereas Au-NPs caused an increase (B). Representative western blot images are depicted on the left; quantification is shown on the right. Co: control. Concentrations were [24.9 µg/mL] for PCL- and PLLA-NPs and [160.3 µg/mL

Deposition of metal particles onto semiconductor nanorods using an ionic liquid

• Michael D. Ballentine,
• Elizabeth G. Embry,
• Marco A. Garcia and
• Lawrence J. Hill

Beilstein J. Nanotechnol. 2019, 10, 718–724, doi:10.3762/bjnano.10.71

• (Figure 1). Quantification of the TEM images confirmed that both samples had similarly sized platinum nanoparticles and a similar number of platinum particles per nanorod (Table 1, a minimum of 100 particles were counted/sized in each case). Using this information, we estimated comparable platinum to

Commercial polycarbonate track-etched membranes as substrates for low-cost optical sensors

• Paula Martínez-Pérez and
• Jaime García-Rupérez

Beilstein J. Nanotechnol. 2019, 10, 677–683, doi:10.3762/bjnano.10.67

• differences in the response depending on the magnitude of such changes, which indicates the utility of PCTE membranes not only for detection, but also for quantification. This work means the discovery of a new, cheap and readily available transducer for the development of optical sensors. Moreover, as

Review of time-resolved non-contact electrostatic force microscopy techniques with applications to ionic transport measurements

• Aaron Mascaro,
• Yoichi Miyahara,
• Tyler Enright,
• Omur E. Dagdeviren and
• Peter Grütter

Beilstein J. Nanotechnol. 2019, 10, 617–633, doi:10.3762/bjnano.10.62

• ionic relaxation. This makes any quantification of the transport properties challenging. To investigate the effect of τPLL on the ability to extract parameters from measured signals, a digitially synthesized voltage waveform varying in time as a stretched exponential (Equation 1, β = 0.7) was applied