Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticles

• Olga Rotan,
• Katharina N. Severin,
• Simon Pöpsel,
• Alexander Peetsch,
• Melisa Merdanovic,
• Michael Ehrmann and
• Matthias Epple

Beilstein J. Nanotechnol. 2017, 8, 381–393, doi:10.3762/bjnano.8.40

• different charge by cells [56][57]. It also underscores the fact that both the cell type as well as the physicochemical properties of a nanoparticle play important roles when it comes to the uptake of nanoparticles by cells [5][55][58][59][60][61][62][63]. The presence of proteins around nanoparticles may

Effect of nanostructured carbon coatings on the electrochemical performance of Li_1.4Ni_0.5Mn_0.5O_2+x-based cathode materials

• Konstantin A. Kurilenko,
• Oleg A. Shlyakhtin,
• Oleg A. Brylev,
• Dmitry I. Petukhov and
• Alexey V. Garshev

Beilstein J. Nanotechnol. 2016, 7, 1960–1970, doi:10.3762/bjnano.7.187

• obtained coatings, which depends on both the organic precursor composition and the preparation conditions. Thus, the investigation of the influence of physicochemical properties of carbon coatings on the electrochemical properties of Li(Ni,Mn,Co)O2+x/C composites proves to be an important task. The choice

“Sticky invasion” – the physical properties of Plantago lanceolata L. seed mucilage

• Agnieszka Kreitschitz,
• Alexander Kovalev and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2016, 7, 1918–1927, doi:10.3762/bjnano.7.183

• see in Figure 2. The deviation from linear dynamics may be related to the decreasing area from which water evaporates and a change in physicochemical properties of the mucilage depending on the water concentration. In two seeds the first phase was shortened to 15 min with followed by two sudden drops

Nanostructured TiO₂-based gas sensors with enhanced sensitivity to reducing gases

• Wojciech Maziarz,
• Anna Kusior and
• Anita Trenczek-Zajac

Beilstein J. Nanotechnol. 2016, 7, 1718–1726, doi:10.3762/bjnano.7.164

• correlation with the obtained results. Conclusion In this work, the crystal structure, morphology and gas sensing properties of the TiO2 nanostructures were investigated. The samples were prepared by chemical and thermal oxidation of Ti substrates. The physicochemical properties of nanostructures with

Properties of Ni and Ni–Fe nanowires electrochemically deposited into a porous alumina template

• Alla I. Vorobjova,
• Dmitry L. Shimanovich,
• Kazimir I. Yanushkevich,
• Sergej L. Prischepa and
• Elena A. Outkina

Beilstein J. Nanotechnol. 2016, 7, 1709–1717, doi:10.3762/bjnano.7.163

• magnetic, electronic, biomedical and optical nano-scale devices [1][2][3][4][5]. Additionally, the magnetic composite nanostructures are interesting as materials for basic research of magnetic and transport properties in magnetic nanosystems as they possess unique physicochemical properties compared with

Development of adsorptive membranes by confinement of activated biochar into electrospun nanofibers

• Mehrdad Taheran,
• Mitra Naghdi,
• Satinder K. Brar,
• Emile Knystautas,
• Mausam Verma,
• Rao. Y. Surampalli and
• Jose. R. Valero

Beilstein J. Nanotechnol. 2016, 7, 1556–1563, doi:10.3762/bjnano.7.149

• most hydrophilic veterinary pharmaceutical compounds with log Kow = −0.52 [20]. The physicochemical properties of CTC favor its mobility in the environment [32]. In fact, if the adsorptive membrane succeed in removal of CTC, it would be possible to apply for removal of other micropollutants. The CTC

An efficient recyclable magnetic material for the selective removal of organic pollutants

• Clément Monteil,
• Nathalie Bar,
• Agnès Bee and
• Didier Villemin

Beilstein J. Nanotechnol. 2016, 7, 1447–1453, doi:10.3762/bjnano.7.136

• synthesis, the coating of maghemite and a characterization of the physicochemical properties of the material [20][22]. As illustrated in Figure 1, PEIP can be customized to contain more or less phosphonated groups, by varying the percentage of amines modified (P%). Between pH 3 and 10, the zeta potential is

Straightforward and robust synthesis of monodisperse surface-functionalized gold nanoclusters

• Silvia Varela-Aramburu,
• Richard Wirth,
• Chian-Hui Lai,
• Guillermo Orts-Gil and
• Peter H. Seeberger

Beilstein J. Nanotechnol. 2016, 7, 1278–1283, doi:10.3762/bjnano.7.118

• related to Alzheimer’s disease [19]. Gold nanoclusters (NCs) are gold nanoparticles ranging in size between 1 and 3 nm, with interesting physicochemical properties and increased surface area for drug delivery applications [20]. There are several methods to synthesize gold nanoparticles. In addition to the

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• silver and superparamagnetic iron oxide NPs [46] in different biological environments was investigated in adherence to the experimental scheme presented in Figure 1. Characteristics of prepared AgNPs and SPIONs As the first step, the physicochemical properties of freshly synthesized NPs were carefully

• ]. Subsequently, the formation of PC modifies the physicochemical properties of NPs, while proteins may undergo conformational and functional changes [52][53][54][55][56]. Consequently, the presence of proteins in dispersion media alters the physicochemical behavior and stability of NPs. DLS data, shown in Table

• delivery systems [4]. The biomedical applications of AgNPs and SPIONs imply uptake into the body, which consequently leads to interactions with protein-containing biological fluids [5][6]. Therefore, it is of increasing interest to systematically collect detailed information on their physicochemical

3D solid supported inter-polyelectrolyte complexes obtained by the alternate deposition of poly(diallyldimethylammonium chloride) and poly(sodium 4-styrenesulfonate)

• Eduardo Guzmán,
• Armando Maestro,
• Sara Llamas,
• Jesús Álvarez-Rodríguez,
• Francisco Ortega,
• Ángel Maroto-Valiente and
• Ramón G. Rubio

Beilstein J. Nanotechnol. 2016, 7, 197–208, doi:10.3762/bjnano.7.18

• their role during film formation is critical for controlling the structure and physicochemical properties of the films [13]. Among the most relevant variables are the charge density of the molecules, the concentration of the solution used, ionic strength, solvent quality for the molecules, pH, and

Nanoinformatics for environmental health and biomedicine

• Rong Liu and
• Yoram Cohen

Beilstein J. Nanotechnol. 2015, 6, 2449–2451, doi:10.3762/bjnano.6.253

• the latest related developments/applications for environmental health and biomedicine. In this Thematic Series, recent advances in the development of databases are reported. These databases represent a collection of valuable data related to the physicochemical properties and bioactivity of

Nanostructured surfaces by supramolecular self-assembly of linear oligosilsesquioxanes with biocompatible side groups

• Maria Nowacka,
• Anna Kowalewska and
• Tomasz Makowski

Beilstein J. Nanotechnol. 2015, 6, 2377–2387, doi:10.3762/bjnano.6.244

• substrate also defines the structure of the assemblies of LPSQ-COOH on mica [37]. It was thus of interest to study if the morphology of the surface layer of PSAMs and its physicochemical properties can be changed by alteration of the mechanism of adsorption on mica. The structure of the PSAMs was engineered

Silica-coated upconversion lanthanide nanoparticles: The effect of crystal design on morphology, structure and optical properties

• Uliana Kostiv,
• Miroslav Šlouf,
• Hana Macková,
• Alexander Zhigunov,
• Hana Engstová,
• Katarína Smolková,
• Petr Ježek and
• Daniel Horák

Beilstein J. Nanotechnol. 2015, 6, 2290–2299, doi:10.3762/bjnano.6.235

• enable further functionalization and increase biocompatibility and stability in aqueous media, preventing particle aggregation. Keywords: lanthanide; nanoparticles; oleylamine; silica; upconversion; Introduction Due to their unique physicochemical properties, nanometer-scale materials are finding

Selective porous gates made from colloidal silica nanoparticles

• Roberto Nisticò,
• Paola Avetta,
• Paola Calza,
• Debora Fabbri,
• Giuliana Magnacca and
• Dominique Scalarone

Beilstein J. Nanotechnol. 2015, 6, 2105–2112, doi:10.3762/bjnano.6.215

• order depending on the physicochemical properties of the block copolymer [38]. Next to the widespread spherical and short cylindrical (rod-like) micellar systems, also other types of supramolecular organizations were found, like lamellar sheets [39], worm-like systems [27] and vesicles [38]. When

Nanofibers for drug delivery – incorporation and release of model molecules, influence of molecular weight and polymer structure

• Jakub Hrib,
• Jakub Sirc,
• Radka Hobzova,
• Zuzana Hampejsova,
• Zuzana Bosakova,
• Marcela Munzarova and
• Jiri Michalek

Beilstein J. Nanotechnol. 2015, 6, 1939–1945, doi:10.3762/bjnano.6.198

• , elemental analysis, IR spectroscopy and melting point measurements. The needle-free electrospinning process was optimized for each type of nanofiber with respect to the different physicochemical properties of polymers. SEM images revealed that the textures of all resultant samples were homogenous and free

• of heterogeneities or artifacts (Figure 2a–c). It can be expected that the addition of PEGs will change the physicochemical properties of the polymer solution in electrospinning, however, it was not noticeable in concentration of PEG 3%. The addition of PEG molecules to the electrospun mixture did

Temperature-dependent breakdown of hydrogen peroxide-treated ZnO and TiO₂ nanoparticle agglomerates

• Sinan Sabuncu and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2015, 6, 1897–1903, doi:10.3762/bjnano.6.193

• devices due to their unique physicochemical properties. One of the major problems with their widespread implementation is their uncontrolled agglomeration. One approach to reduce agglomeration is to alter their surface chemistry with a proper functionality in an environmentally friendly way. In this study

Synthesis, characterization and in vitro biocompatibility study of Au/TMC/Fe₃O₄ nanocomposites as a promising, nontoxic system for biomedical applications

• Hanieh Shirazi,
• Maryam Daneshpour,
• Soheila Kashanian and
• Kobra Omidfar

Beilstein J. Nanotechnol. 2015, 6, 1677–1689, doi:10.3762/bjnano.6.170

• they are considered to be a link between atomic structures and bulk material [4]. Many of the physicochemical properties of materials change as their size approaches the nanoscale, which can be explained by their high surface area to volume ratio and the quantum confinement effect [4][5]. Over the last

The eNanoMapper database for nanomaterial safety information

• Nina Jeliazkova,
• Charalampos Chomenidis,
• Philip Doganis,
• Bengt Fadeel,
• Roland Grafström,
• Barry Hardy,
• Janna Hastings,
• Markus Hegi,
• Vedrin Jeliazkov,
• Nikolay Kochev,
• Pekka Kohonen,
• Cristian R. Munteanu,
• Haralambos Sarimveis,
• Bart Smeets,
• Pantelis Sopasakis,
• Georgia Tsiliki,
• David Vorgrimmler and
• Egon Willighagen

Beilstein J. Nanotechnol. 2015, 6, 1609–1634, doi:10.3762/bjnano.6.165

• , modes of action), interactions (cell lines, assays) and a wide variety of measurements. A number of analytic techniques have been proposed and developed to characterise the physicochemical properties of nanomaterials, including the commonly used dynamic light scattering to measure the particle size

• platform, running on a virtual machine using the VirtualBox software. The wiki contains physicochemical properties and toxicological data for more than three hundred nanomaterials: more than two hundred metal oxides, 80 carbon nanotubes, and a few metal and alloy particles. All nanomaterials originate from

• data dump [27] (in addition to the common MediaWiki XML and SQL dumps of the wiki content). ModNanoTox The ModNanoTox EU FP7 project (http://www.birmingham.ac.uk/generic/modnanotox/index.aspx) has produced a survey and selection of relevant physicochemical properties to use towards building a range of

Influence of surface chemical properties on the toxicity of engineered zinc oxide nanoparticles to embryonic zebrafish

• Zitao Zhou,
• Jino Son,
• Bryan Harper,
• Zheng Zhou and
• Stacey Harper

Beilstein J. Nanotechnol. 2015, 6, 1568–1579, doi:10.3762/bjnano.6.160

• with biological membranes may drive toxicity more than the size of the particle itself. NP agglomeration in aquatic environments often occurs and can be influenced by physicochemical properties of the particle surface and environmental factors affecting the zeta potential [27][45][46]. Therefore, it is

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

• Maria J. Ramalho,
• Joana A. Loureiro,
• Bárbara Gomes,
• Manuela F. Frasco,
• Manuel A. N. Coelho and
• M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

• cell growth, cell cycle arrest and morphological changes. Results Nanoparticle physicochemical properties PLGA NPs were prepared by a single emulsion solvent evaporation method and stabilized with Pluronic®F127. The obtained results for mean the diameter, polydispersity index (PDI) and zeta potential

Synthesis, characterization and in vitro effects of 7 nm alloyed silver–gold nanoparticles

• Simon Ristig,
• Svitlana Chernousova,
• Wolfgang Meyer-Zaika and
• Matthias Epple

Beilstein J. Nanotechnol. 2015, 6, 1212–1220, doi:10.3762/bjnano.6.124

• scientific studies due to their distinct physicochemical properties [1][2]. Apart from their catalytic and optical features, in particular, silver and gold nanoparticles have begun to play a major role in biochemistry, biology and medicine [3][4][5]. Silver nanoparticles are known to be highly toxic towards

• nanoparticles are almost biologically inert (unless they are very small) [13] and therefore widely used in tumor therapy, for drug delivery, or in imaging applications [3][14][15]. In principle, alloyed nanoparticles of silver and gold can combine and utilize the physicochemical properties of both metals, for

• nanoparticles were characterized with respect to their physicochemical properties and their in vitro reaction. Results Nanoparticle characterization Alloyed Ag/Au nanoparticles were synthesized similar to the previously reported synthesis of alloyed Ag/Au 50:50 nanoparticles [30]; however, higher amounts of the

Effects of swift heavy ion irradiation on structural, optical and photocatalytic properties of ZnO–CuO nanocomposites prepared by carbothermal evaporation method

• Sini Kuriakose,
• D. K. Avasthi and
• Satyabrata Mohapatra

Beilstein J. Nanotechnol. 2015, 6, 928–937, doi:10.3762/bjnano.6.96

• ], biosensors [22] and photocatalysts [23][24][25]. Nanocomposites consisting of nanostructures of ZnO and other metal-oxide semiconductors are being widely studied due to their improved physicochemical properties as compared to the individual counterparts. CuO, a p-type narrow band gap semiconductor, is

• promising for applications ranging from solar cells to lithium-ion batteries [26][27][28][29]. ZnO–CuO nanocomposites formed by combining ZnO and CuO nanostructures are expected to exhibit improved physicochemical properties as compared to pure ZnO and CuO nanostructures, because of the formation of nano

• thin films. Swift heavy ion (SHI) irradiation using high electronic excitation is one of the promising techniques used to controllably engineer the size, shape, crystallinity and hence the physicochemical properties of nanostructured materials and nanocomposites. Energetic ions moving in a solid lose

Protein corona – from molecular adsorption to physiological complexity

• Lennart Treuel,
• Dominic Docter,
• Michael Maskos and
• Roland H. Stauber

Beilstein J. Nanotechnol. 2015, 6, 857–873, doi:10.3762/bjnano.6.88

• confirm the previously suggested [22][43][160][161] trivial link between the binding profiles on the NPs and the relative protein concentrations in the plasma. The dynamics of corona formation and composition The physicochemical properties of the protein corona and its evolution with time have been shown

Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques

• Anja Ostrowski,
• Daniel Nordmeyer,
• Alexander Boreham,
• Cornelia Holzhausen,
• Lars Mundhenk,
• Christina Graf,
• Martina C. Meinke,
• Annika Vogt,
• Sabrina Hadam,
• Jürgen Lademann,
• Eckart Rühl,
• Ulrike Alexiev and
• Achim D. Gruber

Beilstein J. Nanotechnol. 2015, 6, 263–280, doi:10.3762/bjnano.6.25

• to be considered when predicting the altered physicochemical properties of the labeled NP, including its charge, size, molecular weight, and overall structure [35]. For example, integrating indocarbocyanine-3 with a molecular weight of 767 Da into nanoscaled macromolecules such as dPGS with a

• molecular weight of 1,300 Da [56] can be expected to drastically alter its physicochemical properties [56]. Consequently, if fluorochromes are integrated into the shell or bound to the surface of a NP, the properties of the new structure are hard to predict and may even alter its behavior in cells and

Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells

• Nils Bohmer and
• Andreas Jordan

Beilstein J. Nanotechnol. 2015, 6, 167–176, doi:10.3762/bjnano.6.16

• ). These modifications resulted in different physicochemical properties referring to SPIONs surface charge and their size distribution under physiological conditions (Table 1). The primary particle size was determined by transmission electron microscopy (EM906, Zeiss). The zeta potential and the average

• [37] and mesoporous silica particles [40] exclusively through Clathrin mediated endocytosis and/or macropinocytosis. This discrepancy can be explained by the different physicochemical properties of the particles used. Especially in the field of iron-oxide nanoparticles more studies concerning the