Comparative study on 3D morphologies of delignified, single tracheids and fibers of five wood species

• Helen Gorges,
• Felicitas von Usslar,
• Cordt Zollfrank,
• Silja Flenner,
• Imke Greving,
• Martin Müller,
• Clemens F. Schaber,
• Chuchu Li and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2026, 17, 239–250, doi:10.3762/bjnano.17.16

• fibers and tracheids, paving the way for more effective modeling applications, such as finite element modeling or computational simulations of fluid flow or heat transfer, aiding in development of various industrial applications of delignified wood. Accurate 3D models provide valuable insights into

Time of flight secondary ion mass spectrometry imaging of contaminant species in chemical vapour deposited graphene on copper

• Barry Brennan,
• Vlad-Petru Veigang-Radulescu,
• Philipp Braeuninger-Weimer,
• Stephan Hofmann and
• Andrew J. Pollard

Beilstein J. Nanotechnol. 2026, 17, 200–213, doi:10.3762/bjnano.17.13

• precursor was introduced for 30 min. The graphene growth atmosphere consisted of 250 SCCM Ar, 26 SCCM H2 and 9 SCCM CH4 (0.1% diluted in Ar) for all samples except the BO sample where a flow rate of 30 SCCM CH4 (0.1% diluted in Ar) was used due to the very low nucleation density. After the growth step the

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• for asymmetric flow field-flow fractionation analysis (AF4 analysis). Experiments were carried out by in-line coupling the AF4 system with UV–vis, multi-angle light scattering (MALS), and dynamic light scattering (DLS) detectors. The AF4 system used was composed of an Eclipse Dualtec separation system

• nm. In the Eclipse SC separation channel, regenerated cellulose membranes (10 kDa) and a spacer height of 350 μm were used. Phosphate buffer was used as the eluent. The detector flow rate was set to 0.5 mL/min and the injection volume was 50 µL. The separation settings were: a) elution 0–3 min; b

• ) focus: 3–5 min (focus flow: 1.0 mL/min); c) focus + injection: 5–10 min (focus flow: 1.0 mL/min); d) elution: 10–50 min (cross-flow: 1.0–0.1 mL/min); e) elution: 50–55 min (cross-flow: 0.1 mL/min); f) elution: 55–60 min (cross-flow: 0.1–0.0 mL/min); g) elution: 60–70 min (cross flow: 0.0 mL/min). The

Development and in vitro evaluation of liposomes and immunoliposomes containing 5-fluorouracil and R-phycoerythrin as a potential phototheranostic system for colorectal cancer

• Raissa Rodrigues Camelo,
• Vivianne Cortez Sombra Vandesmet,
• Octavio Vital Baccallini,
• José de Brito Vieira Neto,
• Thais da Silva Moreira,
• Luzia Kalyne Almeida Moreira Leal,
• Claudia Pessoa,
• Daniel Giuliano Cerri,
• Maria Vitória Lopes Badra Bentley,
• Josimar O. Eloy,
• Ivanildo José da Silva Júnior and
• Raquel Petrilli

Beilstein J. Nanotechnol. 2026, 17, 97–121, doi:10.3762/bjnano.17.7

• nm on a plate spectrophotometer (Nivo-Perkinelmer). The cellular viability was calculated as the percentage of viable cells compared to the control group and half maximum inhibitory concentration (IC50). 2.6.1 Competitive EGFR-binding of anti-EGFR immunoliposome and EGF in HCT-116 cells using flow

• μM) for viable cell selection. Flow cytometry analyses were conducted on a CytoFLEX (Beckman Coulter) using 405 nm and 488 nm lasers to detect DAPI and Alexa Fluor™ 488 signals, respectively. Competitive binding to EGFR was quantified by measuring the cellular fluorescence intensity of Alexa Fluor

Reduced graphene oxide paper electrode for lithium-ion cells – towards optimized thermal reduction

• Agata Pawłowska,
• Magdalena Baran,
• Stefan Marynowicz,
• Aleksandra Izabela Banasiak,
• Adrian Racki,
• Adrian Chlanda,
• Tymoteusz Ciuk,
• Marta Wolczko and
• Andrzej Budziak

Beilstein J. Nanotechnol. 2026, 17, 24–37, doi:10.3762/bjnano.17.3

• applied for thermogravimetric analysis. The measurement was performed in an inert gas flow. The heating rate in this experiment was set to 3 °C/min with a final temperature of 800 °C. The sample was cut to fit the platinum pan. Elemental combustion analysis A LECO O836 analyzer was utilized to determine

Quantitative estimation of nanoparticle/substrate adhesion by atomic force microscopy

• Aydan Çiçek,
• Markus Kratzer,
• Christian Teichert and
• Christian Mitterer

Beilstein J. Nanotechnol. 2026, 17, 1–14, doi:10.3762/bjnano.17.1

• × 10−7 mbar. Ar was introduced as a sputtering gas, keeping a constant flow rate of 40 sccm. Sputtering was carried out at a constant current of 200 mA (≈70 W) applied to the target. The sputtered atoms start to form NPs and to grow in the aggregation zone, where the aggregation length was adjusted to

Internal 3D temperature mapping in biological systems using ratiometric light-sheet imaging and lipid-coated upconversion nanothermometers

• Dannareli Barron-Ortiz,
• Enric Pérez-Parets,
• Rubén D. Cadena-Nava,
• Emilio J. Gualda,
• Jacob Licea-Rodríguez,
• Juan Hernández-Cordero,
• Pablo Loza-Álvarez and
• Israel Rocha-Mendoza

Beilstein J. Nanotechnol. 2025, 16, 2306–2316, doi:10.3762/bjnano.16.159

• 100 µL of UCNPs in a round-bottomed flask. The resulting mixture was then evaporated under a constant flow of N2 gas while stirring in a circular motion for 30 min. After solvent evaporation, 2 mL of Milli-Q water were added to the flask for rehydration overnight at 4 °C. The resulting water

Terahertz-range on-chip local oscillator based on Josephson junction arrays for superconducting quantum-limited receivers

• Fedor V. Khan,
• Lyudmila V. Filippenko,
• Andrey B. Ermakov,
• Mikhail Yu. Fominsky and
• Valery P. Koshelets

Beilstein J. Nanotechnol. 2025, 16, 2296–2305, doi:10.3762/bjnano.16.158

• proven itself for many times both in laboratory and in real-life conditions. The terahertz SIS-mixer integrated on the same chip with the LO based on a flux-flow oscillator (FFO) and a receiving antenna [13] was used to study the irradiation of the human body [15], gas spectroscopy [16], and the

Improving magnetic properties of Mn- and Zn-doped core–shell iron oxide nanoparticles by tuning their size

• Dounia Louaguef,
• Ghouti Medjahdi,
• Sébastien Diliberto,
• Klaus M. Seemann,
• Thomas Gries,
• Joelle Bizeau,
• Damien Mertz,
• Eric Gaffet and
• Halima Alem

Beilstein J. Nanotechnol. 2025, 16, 2285–2295, doi:10.3762/bjnano.16.157

• NPs (see Table 1) and 52.61 mL of benzyl ether (276.77 mol) [14][15]. The mixture was heated under an argon atmosphere (flow rate of ≈100 mL·min−1) at a rate of 5 °C·min−1 to 290 °C and maintained at this temperature for 30 min. After cooling to room temperature under ambient conditions, ethanol (100

• was heated in an argon atmosphere (flow rate of ca. 100 mL·min−1) at a rate of 5 °C·min−1 to 290 °C and maintained at this temperature for 30 min. After cooling to room temperature under ambient conditions, ethanol (100 mL) was added to precipitate the nanoparticles. The resulting black solid was

Optical bio/chemical sensors for vitamin B₁₂ analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks

• Seyed Mohammad Taghi Gharibzahedi and
• Zeynep Altintas

Beilstein J. Nanotechnol. 2025, 16, 2207–2244, doi:10.3762/bjnano.16.153

• ][104][105][106][107][108][109][110][111][112][113][114]. Qin et al. designed a CL sensor to detect VB12, incorporating flow injection analysis, where the catalytic activity of Co2+ released from the VB12 structure acted as the recognition element, luminol served as the indicator luminophore, and the

• hydrogen peroxide (H2O2). The H2O2 is electrochemically produced in real-time by utilizing a negative bias to an electrode, which converts dissolved oxygen in the flow cell. The linear range, LOD, and RSD for the detection of VB12 were 0.001–10 mg/L, 0.0035 mg/L, and less than 3.5%, respectively [102

• efficiency, and ease of implementation [22]. Moreover, Lok et al. assessed VB12 doses in a continuous-flow lab-on-a-chip system based on luminol-peroxide CL tests to monitor Co2+ in the molecular structure of VB12 [24], where the released Co2+ acted as the recognition target, luminol as the indicator

Ultrathin water layers on mannosylated gold nanoparticles

• Maiara A. Iriarte Alonso,
• Jorge H. Melillo,
• Silvina Cerveny,
• Yujin Tong and
• Alexander M. Bittner

Beilstein J. Nanotechnol. 2025, 16, 2183–2198, doi:10.3762/bjnano.16.151

• , we observed a very small number of NPs and higher agglomeration than on APDMES (Figure 6E,F,K,L). Like on APDMES, PEG AuNPs are less uniformly distributed than dimanno-AuNPs. The differences are likely due to the delicate balance between capillary flow and surface interactions. The flow is likely the

• evaporated under nitrogen flow. The VSFG experiments were achieved under dry air flushing at room temperature (24 °C) at four different center frequencies to measure the complete CH and OH stretching region in the broadband infrared. The tunable infrared laser produced femtosecond pulses of ca. 5.5 mW (at

• negative staining, 0.35 µL of dimanno-AuNPs (1.9 × 1013 particles/mL) were deposited on glow-discharged carbon TEM grids (air flow, 20 mA, 4 min). Then, 0.35 µL uranyl acetate (0.5% w/w) was deposited and dried on the sample. AFM imaging AFM topography images were recorded with an Agilent 5500 AFM

Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• transparency, a “Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA) flow diagram (Figure 1) is provided to describe the article selection process. 3 Vulnerability of Himalayan lake ecosystems to microplastic pollution This section presents the environmental setting and vulnerability

• widely used to simulate groundwater flow and contaminant transport processes [20]. Such models have been adapted to cold mountain environments by adding glacier-fed recharge zones, freeze–thaw processes in soils, and topography-induced flow [21]. Semi-distributed models such as SWAT and MIKE SHE have

• also been used regarding Himalayan catchments to simulate subsurface flow and contaminant loading under varying climate and land use scenarios [22]. The models can be used to simulate MP transport in high-altitude lake basins, although particle-bound adaptations are under development. The melting of

Electron transport through nanoscale multilayer graphene and hexagonal boron nitride junctions

• Aleksandar Staykov and
• Takaya Fujisaki

Beilstein J. Nanotechnol. 2025, 16, 2132–2143, doi:10.3762/bjnano.16.147

• . The current is computed for biases in range between 0.0 and 1.0 V with steps of 0.2 V. The computed current for one layer in the Pt/graphene/Pt junction and one layer in the Pt/h-BN/Pt junction is 2.6·10−4 A for 1.0 V of applied bias. The results are identical and, for one layer, the current flow

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• strain, offering critical information about viscosity, flow characteristics, and structural stability. According to the proposed QTPP, a higher viscosity with pseudoplastic (shear-thinning) behavior is preferred for topical formulations, as it ensures ease application and good retention on the skin

• shown in Figure 10A, the base ME demonstrated Newtonian behavior, with viscosity remaining constant regardless of shear rate or temperature. This is consistent with microemulsions that possess globular or discontinuous droplet structures, which typically exhibit Newtonian flow characteristics [50][51

• , Agilent – Santa Clara, USA) coupled with a mass spectrometer (5977B GC/MSD, Agilent – Santa Clara, USA). Prior to injection, samples were dissolved in 1 mL of n-heptane. The GC system operated with helium as the carrier gas at a flow rate of 1 mL·min−1. The injection and detection temperatures were set at

Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• at room temperature (25 °C) for 30 min under Ar flow. Then the reaction medium was started to be heated and when the reaction medium reached 160 °C, freshly prepared 1-DDT (0.52 mL) and t-DDT (3.52 mL) mixture was rapidly injected into the hot reaction medium under vigorous stirring. The synthesis

Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• the behavior of chiral guests inside chiral porous host materials and correlate the ESR results to chromatography phenomena, it is important to emphasize that the spectra were recorded under static conditions. In contrast, HPLC operates under dynamic flow using analyte mixtures. Neighboring group

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• optimal core formulation (1% w/w HA, 2% w/w NE) and process parameters (17 kV applied voltage, 6.25 flow rate ratio (0.04 mL/h inner; 0.25 mL/h outer), 12 cm needle-to-collector distance). These conditions provided highly uniform fibers with an average diameter of 439 ± 100 nm, notably 37% larger than

• process variables, such as high voltage, flow rate, and the distance from the Taylor cone to the collector, which significantly impacts nanofiber morphology [17]. Furthermore, selection of the material to be electrospun is crucial, requiring control over key attributes such as molecular weight, polymer

• composition on fiber formation by analyzing the concentrations of the core components and the process flow rate as variables. It was observed that the concentration of NE-βCp in the core had a significant impact on fiber morphology, as illustrated in Figure 2. The presence of NE-βCp led to an increase in the

Quantum circuits with SINIS structures

• Mikhail Tarasov,
• Mikhail Fominskii,
• Aleksandra Gunbina,
• Artem Krasilnikov,
• Maria Mansfeld,
• Dmitrii Kukushkin,
• Andrei Maruhno,
• Valeria Ievleva,
• Mikhail Strelkov,
• Daniil Zhogov,
• Konstantin Arutyunov,
• Vyacheslav Vdovin,
• Vladislav Stolyarov and
• Valerian Edelman

Beilstein J. Nanotechnol. 2025, 16, 1931–1941, doi:10.3762/bjnano.16.134

• (exceeding the value of Δ − eV) move from the metal to the superconductor, and those with lower energy remain in the normal metal. As a result, a heat flow arises from the normal metal (P is the power of electron cooling) [26]: where Q is the total power released in the superconductor, IV is the Joule heat

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• . Intravenous administration of aEGFR-LNPs at 0.4 mg·kg−1 in pregnant mice resulted in a nearly twofold increase in mRNA expression in placentas compared to antibody-free LNPs, without detectable fetal transfer. Flow cytometry also confirmed a twofold increase in aEGFR-LNP uptake in EGFR+ trophoblasts and

Programmable soliton dynamics in all-Josephson-junction logic cells and networks

• Vsevolod I. Ruzhickiy,
• Anastasia A. Maksimovskaya,
• Sergey V. Bakurskiy,
• Andrey E. Schegolev,
• Maxim V. Tereshonok,
• Mikhail Yu. Kupriyanov,
• Nikolay V. Klenov and
• Igor I. Soloviev

Beilstein J. Nanotechnol. 2025, 16, 1883–1893, doi:10.3762/bjnano.16.131

• can be achieved through alternative means, such as by creating a local mismatch in the damping parameter, for instance, by increasing α from 1 to 3 for one of the series junctions instead of the critical current. The ability to enforce a specific direction of soliton flow makes the soliton diode an

• mechanism would depend on the incorporation of KICKs into specific segments of these all-JJTLs. By programming each KICK to be in either its Open mode (transmitting) or Close mode (blocking), one could control the flow of solitons through the network and define a unique path from any input to any output. To

• functionality would be predicated on the synergistic action of its core components. First, KICKs integrated into the line segments would act as programmable switches controlling the signal flow. Second, the directionality of soliton propagation would be rigorously enforced by integrated soliton diodes. Thus

Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• , which may be due to the fact that the aptamer was not modified and was easily degraded by nucleases. The cytotoxicity of Te4 to TE-1 and HEEC cells showed no potential as a therapeutic agent for EC alone. In addition, Te4 target has been identified as a membrane protein only by flow cytometry, and the

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• Technologies, USA). The column used was a SP®-2560 capillary GC column (100 m × 0.25 mm × 0.20 µm) (Supelco). The injector temperature was maintained at 230 °C, with helium (He) serving as the carrier gas at a flow rate of 1 mL·min−1. The oven temperature was programmed to increase from 150 to 300 °C at a rate

• Thermogravimetric (TG) and differential scanning calorimetry (DSC) analyses of LO (20.5 mg) were performed using a Simultaneous Thermal Analyzer (STA) 449 F3 Jupiter (NETZSCH, Germany). The samples were scanned from 25 to 700 °C at a heating rate of 10 K·min−1 under a nitrogen (N2) atmosphere with a flow rate of 50

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• mode): In a second experiment, 200 µs pulses of C2H4 were introduced into a 10 sccm O2 flow over a polycrystalline Pd catalyst at 365 °C with a repetition rate of 10 Hz and a total pressure of 3.7 × 10−3 mbar (the local pressure at the sample surface is much higher). The resulting APXP spectra shown in

• reaction cell was designed to replicate commercial ALD conditions, including independent pulsing of precursor gases, laminar flow across the sample, and substrate heating. The setup allows for independent control of precursor and co-reactant exposure and supports a variety of chemistries [60]. ALD is a key

• provides unique insight into surface reactions, charge transfer, and interface stability, which are central to the performance and degradation mechanisms of electrochemical systems. Electrochemical interfaces can be studied by APXPS using two primary cell types, namely, membrane-based flow cells and “dip

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• CXCL9/10 expression in Schwann cells [114]. Particle size and stability of the formulation in the patent were characterized using scanning electron microscopy (SEM). The nanoparticles demonstrated enhanced uptake in HepG2 cells, as confirmed by flow cytometry and confocal microscopy, and achieved a

• editing efficiency, MTT assay, and flow cytometry tests were carried out to observe the therapeutic activity of the technology. The results demonstrated that the nanoparticles increased targeting and internalization, had a knockout rate of 80%, and exhibited better inhibition of HepG2 cell proliferation

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• flow rate of 12 g/10 min and an indicated modulus of 1400 MPa and glass fiber-reinforced polypropylene MP2000 (hereafter abbreviated as PPGF) with 25% glass fiber content, a melt flow rate of 16 g/10 min and an indicated modulus of 4000 MPa (both LyondellBasell, Rotterdam, Netherlands). The reported

• produced. It can be seen that unidirectional and bidirectional gradients can be produced with a straight or V-shaped material interface present. However, it is apparent that, as the glass fiber content decreases, the polymer flow increases (Figure 3C, bottom and top part) [40], resulting in less clearly