Characterization and influence of hydroxyapatite nanopowders on living cells

• Przemyslaw Oberbek,
• Tomasz Bolek,
• Adrian Chlanda,
• Seishiro Hirano,
• Sylwia Kusnieruk,
• Julia Rogowska-Tylman,
• Ganna Nechyporenko,
• Viktor Zinchenko,
• Wojciech Swieszkowski and
• Tomasz Puzyn

Beilstein J. Nanotechnol. 2018, 9, 3079–3094, doi:10.3762/bjnano.9.286

• Nanomaterials, such as hydroxyapatite nanoparticles show a great promise for medical applications due to their unique properties at the nanoscale. However, there are concerns about the safety of using these materials in biological environments. Despite a great number of published studies of nanoobjects and

• chromatography, protein purification, cell-culture substrates, catalyst production and waste management. Lower crystallinity, high purity and high zeta potential of hydroxyapatite nanoparticles are desired in a material intended for long-term medical use in the body. Since calcium deficiency is a feature of

Size-selected Fe₃O₄–Au hybrid nanoparticles for improved magnetism-based theranostics

• Maria V. Efremova,
• Yulia A. Nalench,
• Eirini Myrovali,
• Anastasiia S. Garanina,
• Ivan S. Grebennikov,
• Polina K. Gifer,
• Maxim A. Abakumov,
• Marina Spasova,
• Makis Angelakeris,
• Alexander G. Savchenko,
• Michael Farle,
• Natalia L. Klyachko,
• Alexander G. Majouga and
• Ulf Wiedwald

Beilstein J. Nanotechnol. 2018, 9, 2684–2699, doi:10.3762/bjnano.9.251

• State University, Moscow, 119991, Russia National University of Science and Technology «MISIS», Moscow, 119049, Russia Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece Department of Medical Nanobiotechnology, Russian National Research Medical University, Moscow

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe₂O₃ nanoparticles towards human tumor cells

• Zdeněk Plichta,
• Yulia Kozak,
• Rostyslav Panchuk,
• Viktoria Sokolova,
• Matthias Epple,
• Lesya Kobylinska,
• Pavla Jendelová and
• Daniel Horák

Beilstein J. Nanotechnol. 2018, 9, 2533–2545, doi:10.3762/bjnano.9.236

• Biology, NAS of Ukraine, Drahomanov Str. 14/16, Lviv 79005, Ukraine Inorganic Chemistry and Center for Nanointegration, University of Duisburg-Essen, Universitaetsstr. 5-7, D-45117 Essen, Germany Danylo Halytsky Lviv National Medical University, Pekarska Str. 69, Lviv 79000, Ukraine Institute of

• Mouse melanoma cells of B16F10/wt line, human T-leukemia cells of Jurkat, K562, HL-60 lines and its drug-resistant HL-60/vinc sub-line (overexpression of P-glycoprotein) were a kind gift of Prof. Walter Berger, Institute of Cancer Research, Vienna Medical University (Austria). Human mesenchymal stem

• oxide particles used in the MTT test. Acknowledgements Financial support of the Czech Science Foundation (No. 17-04918S) is acknowledged. We thank Cedars-Sinai Medical Center’s International Research and Innovation in Medicine Program and the Association for Regional Cooperation in the Fields of Health

Enhanced antineoplastic/therapeutic efficacy using 5-fluorouracil-loaded calcium phosphate nanoparticles

• Shanid Mohiyuddin,
• Saba Naqvi and
• Gopinath Packirisamy

Beilstein J. Nanotechnol. 2018, 9, 2499–2515, doi:10.3762/bjnano.9.233

• problems in medical prognoses such as nonspecific cytotoxicity, insignificant survival rate, re-initialization of cancer, in vitro evolution of multidrug resistance, and unwanted side effects [2]. The failure of conventional therapeutic strategies indicates that additional efforts should be focused

Droplet-based synthesis of homogeneous magnetic iron oxide nanoparticles

• Christian D. Ahrberg,
• Ji Wook Choi and
• Bong Geun Chung

Beilstein J. Nanotechnol. 2018, 9, 2413–2420, doi:10.3762/bjnano.9.226

• properties. In medical applications, for example, magnetic nanoparticles can be used for targeting, imaging, magnetically induced thermotherapy, or for any combination of the three. However, it is still a challenge to obtain narrowly dispersed, reproducible particles through a typical lab-scale synthesis

• storage [2], environmental studies [3], or in medicine [4]. In medical applications, a particular focus of research lies on the development of multifunctional nanomaterials, as they allow for the parallel treatment and diagnostic monitoring of a diseases and thus would help to reduce the costs of

Fabrication of photothermally active poly(vinyl alcohol) films with gold nanostars for antibacterial applications

• Mykola Borzenkov,
• Maria Moros,
• Claudia Tortiglione,
• Serena Bertoldi,
• Nicola Contessi,
• Silvia Faré,
• Angelo Taglietti,
• Agnese D’Agostino,
• Piersandro Pallavicini,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2018, 9, 2040–2048, doi:10.3762/bjnano.9.193

• -forming properties [11][12]. All these properties encouraged extensive investigations focused on fabrication of a diversity of PVA-based materials for various industrial and medical applications, including food packaging materials, wound dressing substrates, etc. [13][14][15][16]. In addition, numerous

Recent highlights in nanoscale and mesoscale friction

• Andrea Vanossi,
• Dirk Dietzel,
• Andre Schirmeisen,
• Ernst Meyer,
• Rémy Pawlak,
• Thilo Glatzel,
• Marcin Kisiel,
• Shigeki Kawai and
• Nicola Manini

Beilstein J. Nanotechnol. 2018, 9, 1995–2014, doi:10.3762/bjnano.9.190

• technological impact. For example, the treatment of surfaces with molecular layers can have beneficial effects as it is well known from PTFE-coated surfaces. There is a need of alternative coatings for modern touch screens to prevent fingerprints and other contaminants. Surfaces for medical applications are

Biomimetic and biodegradable cellulose acetate scaffolds loaded with dexamethasone for bone implants

• Aikaterini-Rafailia Tsiapla,
• Varvara Karagkiozaki,
• Veroniki Bakola,
• Foteini Pappa,
• Panagiota Gkertsiou,
• Eleni Pavlidou and
• Stergios Logothetidis

Beilstein J. Nanotechnol. 2018, 9, 1986–1994, doi:10.3762/bjnano.9.189

• are placed as coatings in medical devices in order to enhance the biocompatibility [2][3][4]. One technique to produce such coatings is electrospinning, which yields long micro- and nanofibers [5]. More specifically, physical and synthetic polymeric fibers of 30–20000 nm in length are produced by

• three-dimensional (3D) polymeric scaffolds acting as substrates for the growth, differentiation and proliferation of biological cells for their successful implementation in medical devices. This has led to the development of a new generation of diagnostic and therapeutic approaches [12][13]. Although

Synthesis of carbon nanowalls from a single-source metal-organic precursor

• André Giese,
• Sebastian Schipporeit,
• Volker Buck and
• Nicolas Wöhrl

Beilstein J. Nanotechnol. 2018, 9, 1895–1905, doi:10.3762/bjnano.9.181

• superhydrophilic properties, which has a significant effect on cell growth, making CNWs an interesting material for biotechnology (bio-sensors) and medical technology (implants, diagnostics) [13][17]. The growth of CNWs is often referred to as a three-stage process that was originally proposed by Kondo and co

Synthesis of hafnium nanoparticles and hafnium nanoparticle films by gas condensation and energetic deposition

• Irini Michelakaki,
• Nikos Boukos,
• Dimitrios A. Dragatogiannis,
• Spyros Stathopoulos,
• Costas A. Charitidis and
• Dimitris Tsoukalas

Beilstein J. Nanotechnol. 2018, 9, 1868–1880, doi:10.3762/bjnano.9.179

• cross section in neutron absorption [32]. Hafnium alloys are used in medical applications because they are biocompatible and exhibit high corrosion resistance as well as in aerospace technology because it can increase the mechanical strength of materials [33]. Furthermore, because of its high dielectric

Cryochemical synthesis of ultrasmall, highly crystalline, nanostructured metal oxides and salts

• Elena A. Trusova and
• Nikolai S. Trutnev

Beilstein J. Nanotechnol. 2018, 9, 1755–1763, doi:10.3762/bjnano.9.166

• industry and have applications in medical and biological research. Sergeev et al. have shown that the particle size is an active variable that together with other thermodynamic variables determines the state and reactivity of the system, whereby nanoparticles can promote chemical reactions which are not

Tailoring polarization and magnetization of absorbing terahertz metamaterials using a cut-wire sandwich structure

• Hadi Teguh Yudistira,
• Shuo Liu,
• Tie Jun Cui and
• Han Zhang

Beilstein J. Nanotechnol. 2018, 9, 1437–1447, doi:10.3762/bjnano.9.136

• unique properties, such as being non-ionizing and subject to considerably less Rayleigh scattering than the visible or infrared spectrum [1]. The terahertz spectrum has been widely used in research fields such as medical imaging [1][2][3] and security applications [4]. Optical [5][6][7] and microwave

Preparation and morphology-dependent wettability of porous alumina membranes

• Dmitry L. Shimanovich,
• Alla I. Vorobjova,
• Daria I. Tishkevich,
• Alex V. Trukhanov,
• Maxim V. Zdorovets and
• Artem L. Kozlovskiy

Beilstein J. Nanotechnol. 2018, 9, 1423–1436, doi:10.3762/bjnano.9.135

• biotechnological and medical development. Some applications include the separation of organic macromolecules and proteins (bio-filtration), their use in biosensor devices and capsule drug delivery systems, use for coating implants, and as a matrix for the formation of biocompatible tissues [19][20][21][22

Colorimetric detection of Cu²⁺ based on the formation of peptide–copper complexes on silver nanoparticle surfaces

• Gajanan Sampatrao Ghodake,
• Surendra Krishna Shinde,
• Rijuta Ganesh Saratale,
• Avinash Ashok Kadam,
• Ganesh Dattatraya Saratale,
• Asad Syed,
• Fuad Ameen and
• Dae-Young Kim

Beilstein J. Nanotechnol. 2018, 9, 1414–1422, doi:10.3762/bjnano.9.134

• , Goyang-si, Gyeonggi-do, Republic of Korea Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, 32, Dongguk-ro, Ilsandong-gu, Goyang-si, Gyonggido, 10326, Republic of Korea Department of Food Science and Biotechnology, Dongguk University-Seoul, Ilsandong-gu, Goyang-si

Nanoporous silicon nitride-based membranes of controlled pore size, shape and areal density: Fabrication as well as electrophoretic and molecular filtering characterization

• Axel Seidenstücker,
• Stefan Beirle,
• Fabian Enderle,
• Paul Ziemann,
• Othmar Marti and
• Alfred Plettl

Beilstein J. Nanotechnol. 2018, 9, 1390–1398, doi:10.3762/bjnano.9.131

• presented measurements of membranes with millions of pores. Permselectivity studies by fluorescence microscopy The main potential of nanoporous membranes will be the sieving of macromolecules in aqueous solution, especially for medical and biological use and even on an industrial scale [15][42][43

Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules

• María Francisca Matus,
• Martín Ludueña,
• Cristian Vilos,
• Iván Palomo and
• Marcelo M. Mariscal

Beilstein J. Nanotechnol. 2018, 9, 1328–1338, doi:10.3762/bjnano.9.126

• in the medical field [13], the applications of PLA are limited, mainly due to its weak hydrophilicity and low drug loading of polar drugs [14]. However, PLA nanoparticles conjugated with hydrophilic molecules like poly(ethylene glycol) (PEG) are a singular kind of functionalized NPs. Several studies

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

• Jaison Jeevanandam,
• Ahmed Barhoum,
• Yen S. Chan,
• Alain Dufresne and
• Michael K. Danquah

Beilstein J. Nanotechnol. 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98

Single-crystalline FeCo nanoparticle-filled carbon nanotubes: synthesis, structural characterization and magnetic properties

• Rasha Ghunaim,
• Maik Scholz,
• Christine Damm,
• Bernd Rellinghaus,
• Rüdiger Klingeler,
• Bernd Büchner,
• Michael Mertig and
• Silke Hampel

Beilstein J. Nanotechnol. 2018, 9, 1024–1034, doi:10.3762/bjnano.9.95

• interesting for different applications. For example, industrial applications which require a high Curie temperature and coercivity (such as magnetic storage devices) and medical applications (where they are considered as good thermo-seed candidates for cancer thermotherapy) could benefit from this enhanced

Cyclodextrin inhibits zinc corrosion by destabilizing point defect formation in the oxide layer

• Abdulrahman Altin,
• Maciej Krzywiecki,
• Adnan Sarfraz,
• Cigdem Toparli,
• Claudius Laska,
• Philipp Kerger,
• Aleksandar Zeradjanin,
• Karl J. J. Mayrhofer,
• Michael Rohwerder and
• Andreas Erbe

Beilstein J. Nanotechnol. 2018, 9, 936–944, doi:10.3762/bjnano.9.86

• conversion [9]. β-CD is not surface-active [10]. Although the use in food, medical, and pharmaceutical applications, including drug delivery, is well documented [11], application of CDs in corrosion protection is rare [8][12][13][14]. These applications mostly use CDs to solubilize hydrophobic corrosion

Noble metal-modified titania with visible-light activity for the decomposition of microorganisms

• Maya Endo,
• Zhishun Wei,
• Kunlei Wang,
• Baris Karabiyik,
• Kenta Yoshiiri,
• Paulina Rokicka,
• Bunsho Ohtani,
• Agata Markowska-Szczupak and
• Ewa Kowalska

Beilstein J. Nanotechnol. 2018, 9, 829–841, doi:10.3762/bjnano.9.77

• , clothes and dental treatment). For example, slowly released nanosilver has been used in a variety of domestic appliances, such as washing machines (e.g., Samsung SilverNanoHealth technology). Moreover, antibacterial properties of noble metals have been applied for medical purposes, including healing of

Ultralight super-hydrophobic carbon aerogels based on cellulose nanofibers/poly(vinyl alcohol)/graphene oxide (CNFs/PVA/GO) for highly effective oil–water separation

• Zhaoyang Xu,
• Huan Zhou,
• Sicong Tan,
• Xiangdong Jiang,
• Weibing Wu,
• Jiangtao Shi and
• Peng Chen

Beilstein J. Nanotechnol. 2018, 9, 508–519, doi:10.3762/bjnano.9.49

• ]. Therefore, CNFs can potentially be an excellent nanofiber for high-performance polymer nanocomposites, thereby presenting unprecedented opportunities for the development of durable engineering materials from a renewable resource for structural, consumer, and medical applications [11][12]. There is a long

Electron interaction with copper(II) carboxylate compounds

• Michal Lacko,
• Peter Papp,
• Iwona B. Szymańska,
• Edward Szłyk and
• Štefan Matejčík

Beilstein J. Nanotechnol. 2018, 9, 384–398, doi:10.3762/bjnano.9.38

• medical applications because copper exhibits antibacterial and antifungal properties [28]. In FEBID experiments, the deposited Cu–C lines and squares, obtained from the fluorinated copper(II) β-diketonate [Cu(hfac)2], had an atomic ratio of approximately Cu/C/O/F = 10:64:25:1. In materials obtained using

BN/Ag hybrid nanomaterials with petal-like surfaces as catalysts and antibacterial agents

• Konstantin L. Firestein,
• Denis V. Leybo,
• Alexander E. Steinman,
• Andrey M. Kovalskii,
• Andrei T. Matveev,
• Anton M. Manakhov,
• Irina V. Sukhorukova,
• Pavel V. Slukin,
• Nadezda K. Fursova,
• Sergey G. Ignatov,
• Dmitri V. Golberg and
• Dmitry V. Shtansky

Beilstein J. Nanotechnol. 2018, 9, 250–261, doi:10.3762/bjnano.9.27

• the production of cost-effective, scalable, and biologically safe BN/Ag HNMs with pronounced antibacterial and catalytic characteristics for future medical and advanced “green” energy applications. Summing up, all the above described tests and structural studies have confirmed that synthesised BN/Ag

Liquid-crystalline nanoarchitectures for tissue engineering

• Baeckkyoung Sung and
• Min-Ho Kim

Beilstein J. Nanotechnol. 2018, 9, 205–215, doi:10.3762/bjnano.9.22

• striving for decades to invent biocompatible LC nanostructures for biomedical applications [6][7]. These works cover medical imaging and spectroscopy instruments [8][9], diagnostic biosensors [10], microlens devices [11], soft actuators [12][13], and drug delivery systems [14][15]. On the other hand, LCs

• been reported [106]. Lamellar phase PLA-b-PEG-b-PLA hydrogels can be made to exhibit better biodegradability and higher swelling behavior than isotropic gels for medical purposes [107]. Thermotropic copolyester materials in nematic order can be also synthesized to be used as a bioresorbable and tissue

Hyperthermic intracavitary nanoaerosol therapy (HINAT) as an improved approach for pressurised intraperitoneal aerosol chemotherapy (PIPAC): Technical description, experimental validation and first proof of concept

• Daniel Göhler,
• Stephan Große,
• Alexander Bellendorf,
• Thomas Albert Falkenstein,
• Mehdi Ouaissi,
• Jürgen Zieren,
• Michael Stintz and
• Urs Giger-Pabst

Beilstein J. Nanotechnol. 2017, 8, 2729–2740, doi:10.3762/bjnano.8.272

• placed and fixed at all four extremities in a stable supine position similar to the sketch given in Figure 4. An infraumbilical minilaparotomy was performed to insert trocar T1 (Kii®Balloon Blunt Tip System, 12 mm, Applied Medical, Rancho Santa Margarita, CA, USA) into the abdominal cavity (peritoneal

• temperature of 28 °C due to postmortem cooling). Trocar T1 serves firstly to establish a capnoperitoneum (pC = 12 mmHg = 1.6 kPa) that was maintained constant over time by means of an insufflator (UHI-3, Olympus medical life science and industrial divisions, Olympus Australia, Notting Hill, Australia

• ). Afterwards a video endoscope (5 mm 30°, Karl Storz GmbH & Co KG, Tuttlingen, Germany) was fed through trocar T1 for the visual control of a second minilaparotomy at the left lateral-hemi abdomen, where trocar T2 (Kii®Balloon Blunt Tip System, 5 mm, Applied Medical, Rancho Santa Margarita, CA, USA) was