6 article(s) from Desenko, Sergey M
Graphical Abstract
Scheme 1: Synthesis of tetrahydroazolopyrimidine derivatives.
Scheme 2: Various multicomponent reactions involving pyruvic acids (pyruvates) and different α-aminoazoles.
Scheme 3: Synthesis of 4-arylamino-substituted tetrahydroquinolines.
Scheme 4: Ultrasound-assisted multicomponent reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-car...
Scheme 5: Synthesis of 3-cyano-7-(4-methoxyphenyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acid (7)....
Scheme 6: Proposed reaction mechanism.
Figure 1: Alternative structures A and B for the tetrahydroazolopyrimidines 4.
Figure 2: Molecular structure of ethyl 5-(4-bromophenyl)-3-cyano-7-((4-cyano-1H-pyrazol-5-yl)amino)-4,5,6,7-t...
Figure 3: Chains of 4g molecules in the crystal phase.
Graphical Abstract
Scheme 1: Three synthetic approaches to dihydrotetrazolo[1,5-a]pyrimidines.
Scheme 2: Three-component reaction of 1, 7a,b and 8a–d in water.
Figure 1: Molecular structure of 9a according to X-ray data. Displacement ellipsoids are shown at the 50% pro...
Scheme 3: Three-component reaction of 5-aminotetrazole (1) with formaldehyde (7a) and acetylacetone (10).
Scheme 4: a) Three-component reaction of 5-aminotetrazole (1) with acetaldehyde (7b) and ethyl 4,4,4-trifluor...
Graphical Abstract
Scheme 1: An overview of heterocyclic acids used in the Ugi reaction.
Scheme 2: Synthesis of pyrazolopyridine carboxylic acids 4 [45] and 7 [45] in Doebner-type reaction.
Figure 1: Molecular structure of N-(2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl)-6-(4-methoxyphenyl)-3-...
Graphical Abstract
Scheme 1: Aminoazoles in GBB-3CR and Ugi-4CR.
Scheme 2: Reactivity of 5-amino-N-aryl-1H-pyrazole-4-carboxamide and 3-amino-5-methylisoxazole in GBB-3CR and...
Figure 1: Alternative structures A and B for compounds 4 and 6.
Figure 2: Selected data of HSQC and HMBC experiments for compound 4a.
Figure 3: Molecular structure of 3-(tert-butylamino)-2-(4-chlorophenyl)-N-(4-fluorophenyl)-1H-imidazo[1,2-b]p...
Figure 4: Selected data of NOE and HSQC experiments for compound 9d.
Figure 5: Molecular structure of N-(2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl)-N-(5-methylisoxazol-3-...
Graphical Abstract
Scheme 1: Some three-component reactions involving N-aryl-3-oxobutanamides.
Scheme 2: Some Biginelli-type three-component condensations with salicylaldehyde.
Scheme 3: Three-component heterocyclization of 5-amino-3-methylisoxazole (1), salicylaldehyde (2) and N-(2-me...
Figure 1: The possible structure of an intermediate complex in reactions forming the heterocycles 6.
Scheme 4: Possible pathways for the three-component reaction of 5-amino-3-methylisoxazole (1), salicylaldehyd...
Figure 2: Alternative structures 5a and 5'a for dihydroisoxazolopyridine 5a and selected NOESY correlations.
Figure 3: Alternative structures 6a, 6'a and 6''a for compound 6a.
Figure 4: Selected data from NOESY experiments and relative stereochemistry of stereogenic centers at positio...
Figure 5: Molecular structure of compound 6a according to X-ray diffraction data.
Graphical Abstract
Figure 1: Some MCRs of aminoazoles with controlled switching of the direction.
Figure 2: Some possible products of MCRs involving 4-amino-5-carboxamido-1,2,3-triazole and carbonyl compound...
Scheme 1: Multicomponent and sequential reactions of 4-amino-5-carboxamido-1,2,3-triazole with cyclic ketones....
Scheme 2: Multicomponent and sequential reactions of 4-amino-5-carboxamido-1,2,3-triazole with aldehydes and ...