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Search for "dynamic covalent chemistry" in Full Text gives 12 result(s) in Beilstein Journal of Organic Chemistry.

Selective monoformylation of naphthalene-fused propellanes for methylene-alternating copolymers

  • Kenichi Kato,
  • Tatsuki Hiroi,
  • Seina Okada,
  • Shunsuke Ohtani and
  • Tomoki Ogoshi

Beilstein J. Org. Chem. 2025, 21, 1183–1191, doi:10.3762/bjoc.21.95

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  • well with the observed reactivities and selectivity. Attempted macrocyclization leading to linear polymers Formyl groups have diverse reactivities and enable facile condensation, dynamic covalent chemistry, and so on. In this work, we tried the synthesis of cyclic oligomers composed of naphthalene
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Published 18 Jun 2025

Supramolecular assembly of hypervalent iodine macrocycles and alkali metals

  • Krishna Pandey,
  • Lucas X. Orton,
  • Grayson Venus,
  • Waseem A. Hussain,
  • Toby Woods,
  • Lichang Wang and
  • Kyle N. Plunkett

Beilstein J. Org. Chem. 2025, 21, 1095–1103, doi:10.3762/bjoc.21.87

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  • systems, these macrocycles display dynamic behavior even in the absence of extra anions, with monomers swapping between macrocycles to participate in dynamic covalent chemistry. As a demonstration of even higher supramolecular assemblies, we also showed π-extended HIMs enable the co-assembly of
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Published 30 May 2025

Beyond symmetric self-assembly and effective molarity: unlocking functional enzyme mimics with robust organic cages

  • Keith G. Andrews

Beilstein J. Org. Chem. 2025, 21, 421–443, doi:10.3762/bjoc.21.30

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  • popularization of dynamic covalent chemistry in the 1990s [251][252][253][254][255], macrocycle and cage synthesis using reversible reactions [256][257][258][259] like imine formation (Figure 7A) have led to advances in the synthesis of COFs [223][224] and discrete organic cages [260][261][262][263][264][265
  • catalysis. (A) Examples of dynamic covalent chemistry used to synthesize organic cages. (B) Organic cages are gaining traction as soluble discrete organic cavities with catalytic potential. (C) Control of the coordination sphere of a metal in a robust organic cage pMMO (particulate methane monooxygenase
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Published 24 Feb 2025

A dynamic combinatorial library for biomimetic recognition of dipeptides in water

  • Florian Klepel and
  • Bart Jan Ravoo

Beilstein J. Org. Chem. 2020, 16, 1588–1595, doi:10.3762/bjoc.16.131

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  • ), while AA binds significantly weaker (K ≈ 65–71 M−1). Keywords: artificial receptor; dynamic combinatorial chemistry; dynamic covalent chemistry; molecular recognition; thiolate–disulfide exchange; Introduction Peptides are one of the most abundant and structurally versatile motifs in nature. Thus
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Published 02 Jul 2020

1,2,3-Triazolium macrocycles in supramolecular chemistry

  • Mastaneh Safarnejad Shad,
  • Pulikkal Veettil Santhini and
  • Wim Dehaen

Beilstein J. Org. Chem. 2019, 15, 2142–2155, doi:10.3762/bjoc.15.211

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  • -derived tris(crown ether) host (eTC) via a dynamic covalent chemistry approach involving triple threading and a Grubbs-catalyzed ring-closing metathesis [68]. 1H NMR titration experiments have been used for the identification of co-conformations of the four related stable states of 19. The authors have
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Published 12 Sep 2019

Mechanochemistry of supramolecules

  • Anima Bose and
  • Prasenjit Mal

Beilstein J. Org. Chem. 2019, 15, 881–900, doi:10.3762/bjoc.15.86

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  • interactions of alternating hydrophilic and hydrophobic units in the peptide chains played the vital role in the system. Friščić and Aav with co-workers reported the first solvent-free mechanochemical synthesis of hemicucurbiturils [90] through the anion template effect of dynamic covalent chemistry [47][91
  • thermodynamic control. Preferential formation of hexamer 33 under mechanochemical shaking via non-covalent interactions of peptide chains. Anion templated mechanochemical synthesis of macrocycles cycHC[n] by validating the concept of dynamic covalent chemistry. Hydrogen-bond-assisted [2 + 2]-cycloaddition
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Published 12 Apr 2019

Synthesis and post-functionalization of alternate-linked-meta-para-[2n.1n]thiacyclophanes

  • Wout De Leger,
  • Koen Adriaensen,
  • Koen Robeyns,
  • Luc Van Meervelt,
  • Joice Thomas,
  • Björn Meijers,
  • Mario Smet and
  • Wim Dehaen

Beilstein J. Org. Chem. 2018, 14, 2190–2197, doi:10.3762/bjoc.14.192

Graphical Abstract
  • homodithiacalix[4]arenes by dynamic covalent chemistry [12][13][14]. Functionalization of homothiacalix[4]arenes was made possible by changing the precursors before macrocyclization (Scheme 1) [12]. Recently, pillar[n]arenes have attracted much interest as new supramolecular receptors due to their pillar-shaped
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Published 22 Aug 2018

Coordination-driven self-assembly vs dynamic covalent chemistry: versatile methods for the synthesis of molecular metallarectangles

  • Li-Li Ma,
  • Jia-Qin Han,
  • Wei-Guo Jia and
  • Ying-Feng Han

Beilstein J. Org. Chem. 2018, 14, 2027–2034, doi:10.3762/bjoc.14.178

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  • self-assembly; dynamic covalent chemistry; half-sandwich rhodium complex; metallarectangles; one-pot reaction; supramolecular chemistry; Introduction Over the past two decades, supramolecular structures with organometallic half-sandwich fragments have attracted much attention, including
  • metallarectangle structures in one-pot reactions, thereby reducing both waste and the number of reaction steps. In this work we successfully combine coordination-driven self-assembly and dynamic covalent chemistry through imine bond formation between amines and 4-formylpyridine to construct the desired rectangular
  • covalent chemistry to assemble these metallarectangles, we attempted a further method (Scheme 1, method B) to synthesize these assemblies. As shown in Scheme 1, a dinuclear molecular tweezer complex 2 bearing two pendant aldehyde groups can be formed from the labile ligand complex 1 and 4-formylpyridine
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Published 03 Aug 2018

A journey in bioinspired supramolecular chemistry: from molecular tweezers to small molecules that target myotonic dystrophy

  • Steven C. Zimmerman

Beilstein J. Org. Chem. 2016, 12, 125–138, doi:10.3762/bjoc.12.14

Graphical Abstract
  • that evolve over time or communicate or respond to external or internal stimuli. Dynamic covalent chemistry has moved in this direction [93], and some initial efforts in this area using supramolecular chemistry have also appeared. For example, Andy Wilson’s group reported a sequence of supramolecular
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Published 25 Jan 2016

Assembly of synthetic Aβ miniamyloids on polyol templates

  • Sebastian Nils Fischer and
  • Armin Geyer

Beilstein J. Org. Chem. 2015, 11, 2646–2653, doi:10.3762/bjoc.11.284

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  • the first step of Aβ oligomerization. In the present article, we further develop the idea of systematic variation of the oligomerization degree of Aβ fragments by using dynamic covalent chemistry for the assembly of miniamyloids. The size of a polyol template will limit the aggregation degree of Aβ
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Published 17 Dec 2015

Supramolecular chemistry: from aromatic foldamers to solution-phase supramolecular organic frameworks

  • Zhan-Ting Li

Beilstein J. Org. Chem. 2015, 11, 2057–2071, doi:10.3762/bjoc.11.222

Graphical Abstract
  • ) precursors by forming dynamic hydrazone bonds [79] (Scheme 16). This dynamic covalent chemistry approach allowed for quick synthesis of viologen/TTF-alternating polymers. Driven by the intramolecular donor–acceptor interaction between the TTF and viologen units, the polymers folded into pleated conformations
  • supramolecular devices [88]. It is also noteworthy that the preorganization feature of the amide sequences can remarkably increase the selectivity of macrocyclization [42][51][89]. By making use of the dynamic covalent chemistry approach, we have demonstrated that complicated macrocycles can be obtained in
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Published 02 Nov 2015

Multistep organic synthesis of modular photosystems

  • Naomi Sakai and
  • Stefan Matile

Beilstein J. Org. Chem. 2012, 8, 897–904, doi:10.3762/bjoc.8.102

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  • objective of this brief highlight was to exemplify the synthetic efforts that are often hidden behind short papers on functional systems. Quite extensive multistep synthesis has been covered, followed by innovative surface-initiated polymerization and chemoorthogonal dynamic covalent chemistry. The
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Published 19 Jun 2012
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