Enzymes in biosynthesis

  1. Editor: Prof. Jeroen S. Dickschat
    University of Bonn

Biosynthetic pathways towards natural products usually depend on highly specialized enzymes. This thematic issue calls for manuscripts covering various aspects of biosynthetic enzymes, including (but not limited to) functional characterization, enzyme mechanistic studies, structural work, and mutational investigations. Studies covering the application of enzymes in total synthesis or in the transformation of nonnatural substrate analogs are also welcome.

  • Review
  • Published 21 Jun 2022

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Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 707–721, doi:10.3762/bjoc.18.71

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity

  1. Jamshid Amiri Moghaddam,
  2. Huijuan Guo,
  3. Karsten Willing,
  4. Thomas Wichard and
  5. Christine Beemelmanns
  • Full Research Paper
  • Published 22 Jun 2022

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Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 722–731, doi:10.3762/bjoc.18.72

The stereochemical course of 2-methylisoborneol biosynthesis

  1. Binbin Gu,
  2. Anwei Hou and
  3. Jeroen S. Dickschat
  • Letter
  • Published 08 Jul 2022

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Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 818–824, doi:10.3762/bjoc.18.82

  • Full Research Paper
  • Published 21 Jul 2022

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Beilstein J. Org. Chem. 2022, 18, 881–888, doi:10.3762/bjoc.18.89

  • Full Research Paper
  • Published 25 Jul 2022

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Beilstein J. Org. Chem. 2022, 18, 916–925, doi:10.3762/bjoc.18.91

Understanding the competing pathways leading to hydropyrene and isoelisabethatriene

  1. Shani Zev,
  2. Marion Ringel,
  3. Ronja Driller,
  4. Bernhard Loll,
  5. Thomas Brück and
  6. Dan T. Major
  • Full Research Paper
  • Published 04 Aug 2022

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Beilstein J. Org. Chem. 2022, 18, 972–978, doi:10.3762/bjoc.18.97

Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544

  1. Yin Chen,
  2. Jinqiu Ren,
  3. Ruimin Yang,
  4. Jie Li,
  5. Sheng-Xiong Huang and
  6. Yijun Yan
  • Full Research Paper
  • Published 09 Aug 2022

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Beilstein J. Org. Chem. 2022, 18, 1009–1016, doi:10.3762/bjoc.18.101

New azodyrecins identified by a genome mining-directed reactivity-based screening

  1. Atina Rizkiya Choirunnisa,
  2. Kuga Arima,
  3. Yo Abe,
  4. Noritaka Kagaya,
  5. Kei Kudo,
  6. Hikaru Suenaga,
  7. Junko Hashimoto,
  8. Manabu Fujie,
  9. Noriyuki Satoh,
  10. Kazuo Shin-ya,
  11. Kenichi Matsuda and
  12. Toshiyuki Wakimoto
  • Full Research Paper
  • Published 10 Aug 2022

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  • Supp. Info
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1017–1025, doi:10.3762/bjoc.18.102

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