Chemical biology
Johann Wolfgang Goethe-Universität Frankfurt am Main
This thematic issue highlights important research in chemical biology in two reviews, eleven full research papers, and two letters. Contributions cover various aspects of this topic, including computational methods in drug discovery, biosynthesis, and computational methods.
See related thematic issues:
GlycoBioinformatics
Celebrating the role of chemistry in the success of oligonucleotides as therapeutics
Chemical ecology
A detailed view on 1,8-cineol biosynthesis by Streptomyces clavuligerus
- Jan Rinkel,
- Patrick Rabe,
- Laura zur Horst and
- Jeroen S. Dickschat
Beilstein J. Org. Chem. 2016, 12, 2317–2324, doi:10.3762/bjoc.12.225
Computational methods in drug discovery
- Sumudu P. Leelananda and
- Steffen Lindert
Beilstein J. Org. Chem. 2016, 12, 2694–2718, doi:10.3762/bjoc.12.267
A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis
- Daniel Braga,
- Dirk Hoffmeister and
- Markus Nett
Beilstein J. Org. Chem. 2016, 12, 2766–2770, doi:10.3762/bjoc.12.274
Chemical probes for competitive profiling of the quorum sensing signal synthase PqsD of Pseudomonas aeruginosa
- Michaela Prothiwa,
- Dávid Szamosvári,
- Sandra Glasmacher and
- Thomas Böttcher
Beilstein J. Org. Chem. 2016, 12, 2784–2792, doi:10.3762/bjoc.12.277
Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934
- Veronika Ulrich,
- Clara Brieke and
- Max J. Cryle
Beilstein J. Org. Chem. 2016, 12, 2849–2864, doi:10.3762/bjoc.12.284
A postsynthetically 2’-“clickable” uridine with arabino configuration and its application for fluorescent labeling and imaging of DNA
- Heidi-Kristin Walter,
- Bettina Olshausen,
- Ute Schepers and
- Hans-Achim Wagenknecht
Beilstein J. Org. Chem. 2017, 13, 127–137, doi:10.3762/bjoc.13.16
Versatile synthesis of the signaling peptide glorin
- Robert Barnett,
- Daniel Raszkowski,
- Thomas Winckler and
- Pierre Stallforth
Beilstein J. Org. Chem. 2017, 13, 247–250, doi:10.3762/bjoc.13.27
Revaluation of biomass-derived furfuryl alcohol derivatives for the synthesis of carbocyclic nucleoside phosphonate analogues
- Bemba Sidi Mohamed,
- Christian Périgaud and
- Christophe Mathé
Beilstein J. Org. Chem. 2017, 13, 251–256, doi:10.3762/bjoc.13.28
Polyketide stereocontrol: a study in chemical biology
- Kira J. Weissman
Beilstein J. Org. Chem. 2017, 13, 348–371, doi:10.3762/bjoc.13.39
Solid-phase enrichment and analysis of electrophilic natural products
- Frank Wesche,
- Yue He and
- Helge B. Bode
Beilstein J. Org. Chem. 2017, 13, 405–409, doi:10.3762/bjoc.13.43
Investigation of the action of poly(ADP-ribose)-synthesising enzymes on NAD+ analogues
- Sarah Wallrodt,
- Edward L. Simpson and
- Andreas Marx
Beilstein J. Org. Chem. 2017, 13, 495–501, doi:10.3762/bjoc.13.49
Isoxazole derivatives as new nitric oxide elicitors in plants
- Anca Oancea,
- Emilian Georgescu,
- Florentina Georgescu,
- Alina Nicolescu,
- Elena Iulia Oprita,
- Catalina Tudora,
- Lucian Vladulescu,
- Marius-Constantin Vladulescu,
- Florin Oancea and
- Calin Deleanu
Beilstein J. Org. Chem. 2017, 13, 659–664, doi:10.3762/bjoc.13.65
An eco-compatible strategy for the diversity-oriented synthesis of macrocycles exploiting carbohydrate-derived building blocks
- Sushil K. Maurya and
- Rohit Rana
Beilstein J. Org. Chem. 2017, 13, 1106–1118, doi:10.3762/bjoc.13.110
2-Methyl-2,4-pentanediol (MPD) boosts as detergent-substitute the performance of ß-barrel hybrid catalyst for phenylacetylene polymerization
- Julia Kinzel,
- Daniel F. Sauer,
- Marco Bocola,
- Marcus Arlt,
- Tayebeh Mirzaei Garakani,
- Andreas Thiel,
- Klaus Beckerle,
- Tino Polen,
- Jun Okuda and
- Ulrich Schwaneberg
Beilstein J. Org. Chem. 2017, 13, 1498–1506, doi:10.3762/bjoc.13.148
Remarkable functions of sn-3 hydroxy and phosphocholine groups in 1,2-diacyl-sn-glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by 1H NMR spectroscopy
- Yoshihiro Nishida,
- Mengfei Yuan,
- Kazuo Fukuda,
- Kaito Fujisawa,
- Hirofumi Dohi and
- Hirotaka Uzawa
Beilstein J. Org. Chem. 2017, 13, 1999–2009, doi:10.3762/bjoc.13.196
