pH-Responsive fluorescent supramolecular nanoparticles based on tetraphenylethylene-labelled chitosan and a six-fold carboxylated tribenzotriquinacene

• Nan Yang,
• Yi-Yan Zhu,
• Wei-Xiu Lin,
• Yi-Long Lu and
• Wen-Rong Xu

Beilstein J. Org. Chem. 2023, 19, 635–645, doi:10.3762/bjoc.19.45

• supramolecular systems derived from water-soluble macrocycles, including cyclodextrins (CDs), calix[n]arenes (CXs), cucurbiturils (CBs), and pillararenes have been widely studied [2][6][7][8]. Similar to those macrocyclic acceptors, tribenzotriquinacene (TBTQ) derivatives, a class of versatile host molecules

Heteroleptic metallosupramolecular aggregates/complexation for supramolecular catalysis

• Prodip Howlader and
• Michael Schmittel

Beilstein J. Org. Chem. 2022, 18, 597–630, doi:10.3762/bjoc.18.62

• , organic host molecules such as cyclodextrin [50], pillararenes, and cucurbiturils [51] have been developed in the last decades. Although, these exhibit excellent host–guest encapsulation properties with a variety of organic molecules, there are major drawbacks associated with them: variation of the shape

Synthesis of a new water-soluble hexacarboxylated tribenzotriquinacene derivative and its competitive host–guest interaction for drug delivery

• Man-Ping Li,
• Nan Yang and
• Wen-Rong Xu

Beilstein J. Org. Chem. 2022, 18, 539–548, doi:10.3762/bjoc.18.56

• (CXs), cyclodextrins (CDs), cucurbiturils (CBs), and pillararenes, are of particular interest because they can act as vehicles for anticancer drugs by either self-assembling into nanocarriers [14][15][16] or forming host–guest complexes with anticancer drugs [17][18][19][20]. Tribenzotriquinacene (TBTQ

A resorcin[4]arene hexameric capsule as a supramolecular catalyst in elimination and isomerization reactions

• Tommaso Lorenzetto,
• Fabrizio Fabris and
• Alessandro Scarso

Beilstein J. Org. Chem. 2022, 18, 337–349, doi:10.3762/bjoc.18.38

• structures endowed with catalytic features are full covalent units (e.g., cyclodextrins, cucurbiturils, pillararenes and other derivatives) whose synthesis can be sometimes time consuming. Alternatively, supramolecular catalysts can be obtained through self-assembling units [18][19], metal-ligand components

Synthesis of a novel aminobenzene-containing hemicucurbituril and its fluorescence spectral properties with ions

• Qingkai Zeng,
• Qiumeng Long,
• Jihong Lu,
• Li Wang,
• Yuting You,
• Xiaoting Yuan,
• Qianjun Zhang,
• Qingmei Ge,
• Hang Cong and
• Mao Liu

Beilstein J. Org. Chem. 2021, 17, 2840–2847, doi:10.3762/bjoc.17.195

• intriguing macrocycles have come into our sight, cycloparaphenylenes [2][3][4][5][6][7][8], pillararenes [9][10][11][12], tiaraarenes [13][14], coronaarenes [15][16][17], heteracalixaromatics [18][19], and hemicucurbiturils [20] for instance, and these modified macrocycles have been applied into practical

Insight into functionalized-macrocycles-guided supramolecular photocatalysis

• Minzan Zuo,
• Krishnasamy Velmurugan,
• Kaiya Wang,
• Xueqi Tian and
• Xiao-Yu Hu

Beilstein J. Org. Chem. 2021, 17, 139–155, doi:10.3762/bjoc.17.15

• , calixarenes, and pillararenes. This minireview not only summarizes the role that macrocycles play in photocatalytic reactions but also clarifies the photocatalytic mechanisms. Finally, the future research efforts and new pathways to apply macrocycles and supramolecular hybrid materials in photocatalysis are

• supramolecular hosts (Figure 1); crown ethers (CEs), cyclodextrins (CDs), cucurbiturils (CBs), calixarenes (CAs), and pillararenes (PAs) for various photocatalytic reactions. However, biomolecules and other supramolecular-host-related photocatalytic reactions are not included in this minireview. Generally, a

• their spatial proximity. Pillararene-based photocatalysis Pillararenes are a class of pillar-shaped macrocyclic hosts with the methylene group bridged at the para-position of 2,5-dialkoxybenzene. The size of the cavity can be adjusted by the number of repeating units, i.e., pillar[5]arene or pillar[6

Construction of pillar[4]arene[1]quinone–1,10-dibromodecane pseudorotaxanes in solution and in the solid state

• Xinru Sheng,
• Errui Li and
• Feihe Huang

Beilstein J. Org. Chem. 2020, 16, 2954–2959, doi:10.3762/bjoc.16.245

• the further capping of the pseudorotaxanes to construct rotaxanes. Keywords: host–guest chemistry; pillar[4]arene[1]quinones; pillararenes; pseudorotaxanes; supramolecular chemistry; Introduction Relying on the research of basic science, supramolecular chemistry has become an important mean for

• architectures and chemical topology [12][13][14][15][16][17][18][19][20][21][22][23]. Seeking new systems to produce pseudorotaxanes is currently considered a “hot topic” in supramolecular chemistry. As a new class of supramolecular macrocyclic hosts, pillararenes have received extensive attention in recent

• years due to their unique pillar structures and rich environmental responsiveness [24][25][26][27][28][29]. There are more and more reports on pillararenes complexing with different guest molecules to construct pseudorotaxanes [30][31][32][33][34][35]. Previously, our group first demonstrated that alkyl

Novel macrocycles – and old ones doing new tricks

• Wei Jiang and
• Christoph A. Schalley

Beilstein J. Org. Chem. 2019, 15, 1838–1839, doi:10.3762/bjoc.15.178

• diversified. They are not only tools for studying molecular recognition and molecular machines, but are also key components for sensing, supramolecular catalysis, (chiral) separation, drug delivery, or smart materials. Many new macrocycles have recently been reported, with pillararenes being one of the most

Complexation of 2,6-helic[6]arene and its derivatives with 1,1′-dimethyl-4,4′-bipyridinium salts and protonated 4,4'-bipyridinium salts: an acid–base controllable complexation

• Jing Li,
• Qiang Shi,
• Ying Han and
• Chuan-Feng Chen

Beilstein J. Org. Chem. 2019, 15, 1795–1804, doi:10.3762/bjoc.15.173

• are also the epitome of complex-binding pockets of enzymes [3]. Macrocyclic arenes including calixarenes [4][5], resorcinarenes [6], cyclotriveratrylenes [7][8], pillararenes [9], biphen[n]arenes [10] and others [11][12] are all composed of hydroxy-substituted aromatic rings bridged by methylene or

Synthesis, enantioseparation and photophysical properties of planar-chiral pillar[5]arene derivatives bearing fluorophore fragments

• Guojuan Li,
• Chunying Fan,
• Guo Cheng,
• Wanhua Wu and
• Cheng Yang

Beilstein J. Org. Chem. 2019, 15, 1601–1611, doi:10.3762/bjoc.15.164

• guest receptors [4][5]. Planar-chiral macrocyclic molecules are particularly interesting in the context of the host–guest complexation properties [6][7][8]. Pillararenes are typical examples of this type of compounds and have attracted considerable attention due to their facile chemical synthesis and

Synthesis of new p-tert-butylcalix[4]arene-based polyammonium triazolyl amphiphiles and their binding with nucleoside phosphates

• Vladimir A. Burilov,
• Guzaliya A. Fatikhova,
• Mariya N. Dokuchaeva,
• Ramil I. Nugmanov,
• Diana A. Mironova,
• Pavel V. Dorovatovskii,
• Victor N. Khrustalev,
• Svetlana E. Solovieva and
• Igor S. Antipin

Beilstein J. Org. Chem. 2018, 14, 1980–1993, doi:10.3762/bjoc.14.173

• binding sites offering multipoint interactions with a substrate for the effective complexation [13]. Calix[4]arenes and their thia analogues have many advantages over other macrocycles that are frequently used as synthetic receptors, such as cyclodextrins [14], cucurbiturils [15], and pillararenes [16

Synthesis of diamido-bridged bis-pillar[5]arenes and tris-pillar[5]arenes for construction of unique [1]rotaxanes and bis-[1]rotaxanes

• Ying Han,
• Li-Ming Xu,
• Cui-Yun Nie,
• Shuo Jiang,
• Jing Sun and
• Chao-Guo Yan

Beilstein J. Org. Chem. 2018, 14, 1660–1667, doi:10.3762/bjoc.14.142

• ], cyclodextrin [24][25][26], calixarene [27][28][29] and pillararene have been successfully employed as the wheel subcomponent. Pillararenes are new star macrocyclic compounds with aromatic rings para-bridged by methylene units and have unique tubular shape rather than cone [30][31][32]. In recent years, an

• explosive development on the construction of various supramolecular devices and diverse responsive materials has been reported by using diverse functionalized pillararenes [33][34][35]. Due to easily preparation and suitable cavity, functionalized pillar[5]arenes were widely used as wheel component for