New advances in asymmetric organocatalysis

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Editor: Prof. Radovan Šebesta
Comenius University Bratislava
 
Asymmetric organocatalysis became one of the principal methods for the catalytic synthesis of chiral compounds. This thematic issue in the Beilstein Journal of Organic Chemistry aims to highlight new developments across all subdisciplines of enantioselective organocatalysis. This timely collection of articles deals with methodological advances in both covalent (enamine, iminium, phosphine, carbene, etc.) and noncovalent organocatalytic activations, which are often connected to developments of new catalysts. Important mechanistic and computational studies deepen our understanding of this topic and the underlying processes. The gradual maturation of this field is demonstrated by applications of its methodologies to target molecules synthesis, such as natural products or compounds of medicinal interest.
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New advances in asymmetric organocatalysis

  • Radovan Šebesta

Beilstein J. Org. Chem. 2022, 18, 240–242, doi:10.3762/bjoc.18.28

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Editorial
Published 28 Feb 2022

Chiral isothiourea-catalyzed kinetic resolution of 4-hydroxy[2.2]paracyclophane

  • David Weinzierl and
  • Mario Waser

Beilstein J. Org. Chem. 2021, 17, 800–804, doi:10.3762/bjoc.17.68

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Letter
Published 08 Apr 2021

Organocatalytic asymmetric Michael/acyl transfer reaction between α-nitroketones and 4-arylidenepyrrolidine-2,3-diones

  • Chandrakanta Parida and
  • Subhas Chandra Pan

Beilstein J. Org. Chem. 2021, 17, 1447–1452, doi:10.3762/bjoc.17.100

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Published 14 Jun 2021

Electron-rich triarylphosphines as nucleophilic catalysts for oxa-Michael reactions

  • Susanne M. Fischer,
  • Simon Renner,
  • A. Daniel Boese and
  • Christian Slugovc

Beilstein J. Org. Chem. 2021, 17, 1689–1697, doi:10.3762/bjoc.17.117

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Published 21 Jul 2021

Asymmetric organocatalyzed synthesis of coumarin derivatives

  • Natália M. Moreira,
  • Lorena S. R. Martelli and
  • Arlene G. Corrêa

Beilstein J. Org. Chem. 2021, 17, 1952–1980, doi:10.3762/bjoc.17.128

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Review
Published 03 Aug 2021

Enantioenriched α-substituted glutamates/pyroglutamates via enantioselective cyclopropenimine-catalyzed Michael addition of amino ester imines

  • Zara M. Seibel,
  • Jeffrey S. Bandar and
  • Tristan H. Lambert

Beilstein J. Org. Chem. 2021, 17, 2077–2084, doi:10.3762/bjoc.17.134

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Published 17 Aug 2021

Halides as versatile anions in asymmetric anion-binding organocatalysis

  • Lukas Schifferer,
  • Martin Stinglhamer,
  • Kirandeep Kaur and
  • Olga García Macheño

Beilstein J. Org. Chem. 2021, 17, 2270–2286, doi:10.3762/bjoc.17.145

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Published 01 Sep 2021

Base-free enantioselective SN2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis

  • Mili Litvajova,
  • Emiliano Sorrentino,
  • Brendan Twamley and
  • Stephen J. Connon

Beilstein J. Org. Chem. 2021, 17, 2287–2294, doi:10.3762/bjoc.17.146

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Published 02 Sep 2021

Enantioselective PCCP Brønsted acid-catalyzed aminalization of aldehydes

  • Martin Kamlar,
  • Robert Reiberger,
  • Martin Nigríni,
  • Ivana Císařová and
  • Jan Veselý

Beilstein J. Org. Chem. 2021, 17, 2433–2440, doi:10.3762/bjoc.17.160

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Published 16 Sep 2021

Recent advances in organocatalytic asymmetric aza-Michael reactions of amines and amides

  • Pratibha Sharma,
  • Raakhi Gupta and
  • Raj K. Bansal

Beilstein J. Org. Chem. 2021, 17, 2585–2610, doi:10.3762/bjoc.17.173

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Published 18 Oct 2021

N-Sulfinylpyrrolidine-containing ureas and thioureas as bifunctional organocatalysts

  • Viera Poláčková,
  • Dominika Krištofíková,
  • Boglárka Némethová,
  • Renata Górová,
  • Mária Mečiarová and
  • Radovan Šebesta

Beilstein J. Org. Chem. 2021, 17, 2629–2641, doi:10.3762/bjoc.17.176

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Published 25 Oct 2021

Solvent-free synthesis of enantioenriched β-silyl nitroalkanes under organocatalytic conditions

  • Akhil K. Dubey and
  • Raghunath Chowdhury

Beilstein J. Org. Chem. 2021, 17, 2642–2649, doi:10.3762/bjoc.17.177

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Published 27 Oct 2021

Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins

  • Jiang-Song Zhai and
  • Da-Ming Du

Beilstein J. Org. Chem. 2022, 18, 25–36, doi:10.3762/bjoc.18.3

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Published 04 Jan 2022
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