Mechanochemistry III

Editors:
Prof. José G. Hernández, Universidad de Antioquia
Prof. Lars Borchardt, Ruhr-Universität Bochum

Mechanochemistry III aims at providing the readership with an excellent collection of contributions in the field of mechanochemistry, including mechanosynthesis of organic molecules, catalysis under mechanochemical conditions, mechanistic studies of mechanochemical transformations, polymer mechanochemistry, and much more.

Multi-faceted reactivity of N-fluorobenzenesulfonimide (NFSI) under mechanochemical conditions: fluorination, fluorodemethylation, sulfonylation, and amidation reactions

José G. Hernández,
Karen J. Ardila-Fierro,
Dajana Barišić and
Hervé Geneste

Full Research Paper
Published 07 Feb 2022

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1. Graphical Abstract
2. Scheme 1: Examples of mechanochemical reactions using NFSI.
  
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3. Scheme 2: Mechanochemical fluorination of arenes 1 with NFSI. (a) Product distributions and reaction conditio...
  
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4. Figure 1: Time-resolved 2D plots of the mechanochemical reaction of: (a) 1c (0.59 mmol), NFSI (1.0 equiv), an...
  
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5. Scheme 3: (a–f) Reactions of substrates 3 with NFSI. Reaction conditions: Substrates 3 (0.734 mmol) were mill...
  
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6. Scheme 4: Regioselective C-3 mechanochemical amidation of 5 with NFSI.
  
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Supp. Info

Beilstein J. Org. Chem. 2022, 18, 182–189, doi:10.3762/bjoc.18.20

Full Text

Mechanochemistry III

Multi-faceted reactivity of N-fluorobenzenesulfonimide (NFSI) under mechanochemical conditions: fluorination, fluorodemethylation, sulfonylation, and amidation reactions

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