Carbometallation chemistry

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Editor: Prof. Ilan Marek
Technion – Israel Institute of Technology
 
Following the pioneering Ziegler addition of nucleophiles to nonactivated unsaturated carbon–carbon bonds, the controlled carbometallation reaction has emerged. Since then, reactions that result in the addition of a carbon–metal bond of an organometallic across a carbon–carbon unsaturated system, leading to a new organometallic in which the newly formed carbon–metal bond can be used for further synthetic transformations, are called carbometallation reactions. In the past few decades, the intra- as well as intermolecular additions of various organometallic species to a large variety of alkynes, alkenes and allenes have been successfully reported.
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Carbometallation chemistry

  • Ilan Marek

Beilstein J. Org. Chem. 2013, 9, 234–235, doi:10.3762/bjoc.9.27

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Editorial
Published 04 Feb 2013

Stereoselective synthesis of tetrasubstituted alkenes via a sequential carbocupration and a new sulfur–lithium exchange

  • Andreas Unsinn,
  • Cora Dunst and
  • Paul Knochel

Beilstein J. Org. Chem. 2012, 8, 2202–2206, doi:10.3762/bjoc.8.248

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Letter
Published 18 Dec 2012

Highly stereocontrolled synthesis of trans-enediynes via carbocupration of fluoroalkylated diynes

  • Tsutomu Konno,
  • Misato Kishi and
  • Takashi Ishihara

Beilstein J. Org. Chem. 2012, 8, 2207–2213, doi:10.3762/bjoc.8.249

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Letter
Published 19 Dec 2012

Intramolecular carbolithiation of N-allyl-ynamides: an efficient entry to 1,4-dihydropyridines and pyridines – application to a formal synthesis of sarizotan

  • Wafa Gati,
  • Mohamed M. Rammah,
  • Mohamed B. Rammah and
  • Gwilherm Evano

Beilstein J. Org. Chem. 2012, 8, 2214–2222, doi:10.3762/bjoc.8.250

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Published 21 Dec 2012

Radical zinc-atom-transfer-based carbozincation of haloalkynes with dialkylzincs

  • Fabrice Chemla,
  • Florian Dulong,
  • Franck Ferreira and
  • Alejandro Pérez-Luna

Beilstein J. Org. Chem. 2013, 9, 236–245, doi:10.3762/bjoc.9.28

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Published 04 Feb 2013

Recent advances in transition-metal-catalyzed intermolecular carbomagnesiation and carbozincation

  • Kei Murakami and
  • Hideki Yorimitsu

Beilstein J. Org. Chem. 2013, 9, 278–302, doi:10.3762/bjoc.9.34

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Review
Published 11 Feb 2013

Inter- and intramolecular enantioselective carbolithiation reactions

  • Asier Gómez-SanJuan,
  • Nuria Sotomayor and
  • Esther Lete

Beilstein J. Org. Chem. 2013, 9, 313–322, doi:10.3762/bjoc.9.36

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Review
Published 13 Feb 2013

Regio- and stereoselective carbometallation reactions of N-alkynylamides and sulfonamides

  • Yury Minko,
  • Morgane Pasco,
  • Helena Chechik and
  • Ilan Marek

Beilstein J. Org. Chem. 2013, 9, 526–532, doi:10.3762/bjoc.9.57

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Published 13 Mar 2013
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Published 14 Mar 2013

Carbolithiation of N-alkenyl ureas and N-alkenyl carbamates

  • Julien Lefranc,
  • Alberto Minassi and
  • Jonathan Clayden

Beilstein J. Org. Chem. 2013, 9, 628–632, doi:10.3762/bjoc.9.70

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Published 28 Mar 2013

Intramolecular carbonickelation of alkenes

  • Rudy Lhermet,
  • Muriel Durandetti and
  • Jacques Maddaluno

Beilstein J. Org. Chem. 2013, 9, 710–716, doi:10.3762/bjoc.9.81

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Published 12 Apr 2013
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