7 article(s) from Beier, Petr
Graphical Abstract
Figure 1: Selected pyrrole-containing natural products, drugs, agrochemicals, and functional materials.
Scheme 1: Transformation of N-sulfonyl-1,2,3-triazoles to pyrroles via metal iminocarbenes.
Scheme 2: Transannulation of triazoles 2 with phenylacetylene.
Scheme 3: Transannulation of N-perfluoroalkyl-1,2,3-triazoles with aliphatic alkynes.
Scheme 4: Reaction of 1a with hex-5-ynenitrile.
Scheme 5: Metalation and carboxylation of in situ-prepared pyrrole 2a.
Scheme 6: Plausible mechanism for rhodium-catalyzed transannulation of N-perfluoroalkyl-1,2,3-triazoles with ...
Graphical Abstract
Scheme 1: Synthetic routes for the preparation of trifluoromethyl dithiocarbamates.
Scheme 2: Synthesis of S-trifluoromethyl dithiocarbamates. Isolated yields are given in parentheses.
Scheme 3: Formation of benzyl isothiocyanate in a reaction with benzylamine.
Figure 1: Variable temperature 1H NMR spectra of compound 4c (CH2 region on the left and CH3 region on the ri...
Figure 2: The Eyring plot obtained for the rotation around the N–C bond in compound 4c.
Figure 3: The optimized structure of compound 4b (left) and the transition state structure for the rotation a...
Graphical Abstract
Scheme 1: Direct fluorination of 1,2-bis(3-nitrophenyl)disulfane.
Scheme 2: Direct fluorination of 3-nitro-1-(pentafluorosulfanyl)benzene (1).
Figure 1: Conversion vs added fluorine equivalents for the fluorination of 1 in MeCN (left) and anhydrous HF ...
Scheme 3: Preparative fluorination of 3-nitro-1-(pentafluorosulfanyl)benzene (1).
Scheme 4: Synthesis of 2 by fluorodenitration of 5.
Graphical Abstract
Scheme 1: Oxidation of SF5-anisole and phenol. 19F NMR yields are shown (isolated yields in parentheses).
Scheme 2: Proposed mechanism for the formation of 3 and 4 from SF5 aromatics 1 and 2.
Scheme 3: Oxidation of anisole 10 and phenol 11. 19F NMR yields are given.
Scheme 4: Synthesis of para-benzoquinone 12 and oxidation to maleic acid 4. 19F NMR yields are shown, in pare...
Scheme 5: Catalytic hydrogenation and Diels–Alder reaction of benzoquinone 12.
Figure 1: Optimized geometries of transition states of Diels–Alder reaction of cyclopentadiene with 12. Selec...
Scheme 6: Decomposition of 3 in water.
Scheme 7: Formation of acids 5, 18 and 19 from lactone 3.
Scheme 8: Synthesis of maleic anhydride 20 and Diels–Alder adducts 21.
Scheme 9: Reaction of maleic acid 4 with diazomethane.
Scheme 10: Decarboxylation of maleic acid 4 to acrylic acid 23 in DMSO and the preparation of deuterium labell...
Graphical Abstract
Scheme 1: Borylation of aryldiazonium tetrafluoroborates 3. Reaction conditions: 3 (1 mmol), B2pin2 (1 mmol),...
Scheme 2: Proposed reaction mechanism.
Scheme 3: Reaction of diazonium salt 3i under borylation conditions.
Scheme 4: Suzuki–Miyaura reaction of boronates 2a and 2b with aryl iodides. Reaction conditions: 2 (1 mmol), ...
Scheme 5: Syntesis of boronic acid 8b and trifluoroborates 9. Reaction conditions for the synthesis of 8b: 2 ...
Scheme 6: Iodination of aryldiazonium tetrafluoroborates 3. Reaction conditions: 3 (1 mmol), I2 (1.1 mmol), p...
Graphical Abstract
Scheme 1: Proposed mechanism of the Davis reaction giving benzisoxazoles.
Figure 1: Substitution products 1, oximes 2 and nitro-(pentafluorosulfanyl)benzenes 3 and 4.
Scheme 2: Synthesis of SF5-substituted quinolines and mefloquine analogues by Wipf and co-workers [29,30].
Scheme 3: Synthesis of quinoline 12.
Scheme 4: Synthesis of quinoline 13.
Scheme 5: Synthesis of quinazoline 14.
Graphical Abstract
Scheme 1: Proposed synthesis of alkenyl-(pentafluorosulfanyl)benzenes.
Scheme 2: Reactive intermediates involved in HWE reactions to alkenes 5 and 6.
Scheme 3: Diazotization/reduction of 8d to 9d and the formation of unexpected cyclized product 10d.
Scheme 4: Synthesis of substituted phenanthrene 11d.
Scheme 5: Synthesis of phosphonate 12 and SF5-stilbene derivative 13d.