Search results

Search for "interaction" in Full Text gives 1106 result(s) in Beilstein Journal of Organic Chemistry. Showing first 200.

Chemical and biosynthetic potential of Penicillium shentong XL-F41

  • Ran Zou,
  • Xin Li,
  • Xiaochen Chen,
  • Yue-Wei Guo and
  • Baofu Xu

Beilstein J. Org. Chem. 2024, 20, 597–606, doi:10.3762/bjoc.20.52

Graphical Abstract
  • over 260 secondary metabolites from Penicillium [5], exhibiting not only antibacterial and anticancer activities but also potent antioxidant properties, inhibition of GSK-3β and α-glucosidase activities, and interaction with the pregnane X receptor (PXR). These compounds are categorized into
PDF
Album
Supp Info
Full Research Paper
Published 15 Mar 2024

A myo-inositol dehydrogenase involved in aminocyclitol biosynthesis of hygromycin A

  • Michael O. Akintubosun and
  • Melanie A. Higgins

Beilstein J. Org. Chem. 2024, 20, 589–596, doi:10.3762/bjoc.20.51

Graphical Abstract
  • peptidyl transferase activity while the furanose group does not appear to be important for target inhibition [6][7]. In addition, hygromycin A contains a unique methylenedioxy group found on the aminocyclitol that is not required for ribosome interaction and in vitro inhibition [8]. Instead, it is
PDF
Album
Supp Info
Full Research Paper
Published 14 Mar 2024

Possible bi-stable structures of pyrenebutanoic acid-linked protein molecules adsorbed on graphene: theoretical study

  • Yasuhiro Oishi,
  • Motoharu Kitatani and
  • Koichi Kusakabe

Beilstein J. Org. Chem. 2024, 20, 570–577, doi:10.3762/bjoc.20.49

Graphical Abstract
  • (1.63 eV), than that of conformation 2, which is about 1.28 eV. The stabilization of conformation 1 partly comes from interaction between the succinimidyl ester part and graphene. There are other C–C single bonds in the alkyl chain, such as those shown by the dashed and dotted lines in Figure 1a
  • the DFT calculation realized by the PWscf code of Quantum ESPRESSO [30][31][32], the DFT-D3 correlation [33] together with PBEsol functional [34] for the exchange-correlation functional described van der Waals interaction between graphene and pyrene fragment in PASE. Ultrasoft pseudopotentials [35
  • ] with the energy cutoff of 35 (350) Ry for the expansion of wavefunction (charge density) described the electron-nuclear interaction. Using the 2 × 4 × 1 k-point mesh of Monkhorst–Pack [36], the Brillouin zone sampling was safely performed. Additional details of calculation conditions may be found in a
PDF
Album
Full Research Paper
Published 11 Mar 2024

Entry to new spiroheterocycles via tandem Rh(II)-catalyzed O–H insertion/base-promoted cyclization involving diazoarylidene succinimides

  • Alexander Yanovich,
  • Anastasia Vepreva,
  • Ksenia Malkova,
  • Grigory Kantin and
  • Dmitry Dar’in

Beilstein J. Org. Chem. 2024, 20, 561–569, doi:10.3762/bjoc.20.48

Graphical Abstract
  • of compound 4b has been confirmed by single crystal X-ray data. The next step was to investigate the possibility of obtaining six-membered oxygen-containing spiroheterocycles by interaction of DAS 1 with 2-(bromomethyl)benzyl alcohol (15) (Scheme 6). The synthesis was carried out under the conditions
PDF
Album
Supp Info
Full Research Paper
Published 11 Mar 2024

Synthesis of photo- and ionochromic N-acylated 2-(aminomethylene)benzo[b]thiophene-3(2Н)-ones with a terminal phenanthroline group

  • Vladimir P. Rybalkin,
  • Sofiya Yu. Zmeeva,
  • Lidiya L. Popova,
  • Irina V. Dubonosova,
  • Olga Yu. Karlutova,
  • Oleg P. Demidov,
  • Alexander D. Dubonosov and
  • Vladimir A. Bren

Beilstein J. Org. Chem. 2024, 20, 552–560, doi:10.3762/bjoc.20.47

Graphical Abstract
  • change of the solutions from yellow to dark orange. Subsequent selective interaction with AcO− led to the restoration of the initial absorption and emission properties. Thus, the obtained compounds represent dual-mode “on–off–on” switches of optical and fluorescent properties under sequential exposure to
  • the phenanthroline unit was also involved in a π–π-stacking interaction (blue plane–green plane in Figure 4), with the plane centroid–plane centroid distance being 3.6998(8) Å (plane shift 1.4919(17) Å, twist and fold angles 1.54° and 1.92°, respectively). Cation-induced transformations of the
  • series method, compounds 2a–c formed the 2:1 complexes 4a–c with Fe2+ (Scheme 3 and Figure 7). It was found that selective interaction of the resulting in situ complex 4a with AcO− led to restoration of the initial absorption and emission properties [31][32]. Other tetra-n-butylammonium salts (TBAX, X
PDF
Album
Supp Info
Full Research Paper
Published 11 Mar 2024

Switchable molecular tweezers: design and applications

  • Pablo Msellem,
  • Maksym Dekthiarenko,
  • Nihal Hadj Seyd and
  • Guillaume Vives

Beilstein J. Org. Chem. 2024, 20, 504–539, doi:10.3762/bjoc.20.45

Graphical Abstract
  • proximity, either by direct interaction or via a small intercalating molecule. Therefore, switchable molecular tweezers can be considered a prototype of a mechanical molecular device capable of allosteric regulation and dual control through switching and guest binding. While the primary application of
  • distance of 21 Å between the two Cu(II) complexes results in an independent paramagnetic behavior. However, in the closed form, the metal centers are much closer to each other (4.03 Å) resulting in a weak antiferromagnetic coupling via through-space exchange interaction. This demonstrates the value of
  • by the addition of zinc(II) which opens the tweezers, releasing the guest and leading to the disappearance of the photosensitizing properties of the system. In an extension of this work, discrete tetranuclear Pt complexes with Pt–Pt interaction were obtained by self-assembly between 21 and
PDF
Album
Review
Published 01 Mar 2024

Ligand effects, solvent cooperation, and large kinetic solvent deuterium isotope effects in gold(I)-catalyzed intramolecular alkene hydroamination

  • Ruichen Lan,
  • Brock Yager,
  • Yoonsun Jee,
  • Cynthia S. Day and
  • Amanda C. Jones

Beilstein J. Org. Chem. 2024, 20, 479–496, doi:10.3762/bjoc.20.43

Graphical Abstract
  • 23–27) [53], thus rates do not correlate with N–H acidity either (the least acidic urea is the most active). Interaction of gold(I) with the two functional group types (carbonyl versus sulfonamide) is predicted to differ in a key aspect. Lithiated carbanions alpha to carbonyl functional groups are O
  • support the argument that faster reactions are associated with greater kinetic interaction with the carbonyl nucleophile. Sulfonamide hydroamination has also distinguished itself from urea and carbamate hydroamination in demonstrating productive reactivity with HOTf as a catalyst [31][58]. A few things
  • -workers, it was found that in chlorination reactions, activation of alkenes is not driven by the electrophilicity of the reagent being attacked by an alkene, but instead depends on nucleophile assistance: the alkene becomes more nucleophilic upon interaction with the pendant attacking nucleophile [81]. In
PDF
Album
Supp Info
Full Research Paper
Published 29 Feb 2024

(E,Z)-1,1,1,4,4,4-Hexafluorobut-2-enes: hydrofluoroolefins halogenation/dehydrohalogenation cascade to reach new fluorinated allene

  • Nataliia V. Kirij,
  • Andrey A. Filatov,
  • Yurii L. Yagupolskii,
  • Sheng Peng and
  • Lee Sprague

Beilstein J. Org. Chem. 2024, 20, 452–459, doi:10.3762/bjoc.20.40

Graphical Abstract
  • oxirane [14]. A related study has demonstrated that (E)-butene 1a reacts with potassium persulfate to form 4,5-bistrifluoromethyl)-1,3,2-dioxathiolane 2,2-dioxide [15]. In 2021 Petrov published an article on the interaction of fluorinated olefins with fluorinated thioketones. In this publication it was
  • continues to be relevant. One of the methods for the synthesis of allenes was based on the interaction of bromoolefins with organolithium compounds, followed by the elimination of lithium fluoride [29][30][31]. It was logical to assume that in our case a similar reaction of the Grignard reagent 12 with
PDF
Album
Supp Info
Full Research Paper
Published 27 Feb 2024

Enhanced host–guest interaction between [10]cycloparaphenylene ([10]CPP) and [5]CPP by cationic charges

  • Eiichi Kayahara,
  • Yoshiyuki Mizuhata and
  • Shigeru Yamago

Beilstein J. Org. Chem. 2024, 20, 436–444, doi:10.3762/bjoc.20.38

Graphical Abstract
  • suggested the partial electron transfer from [10]CPP to [5]CPP2+ in the complex, and this charge-transfer (CT) interaction is most likely the origin of the higher association constant of the dicationic complex than the neutral one. Keywords: charge-transfer; cycloparaphenylene; dication; host–guest
  • photophysical and electrochemical analyses and DFT calculations. Therefore, this CT is most likely the origin of the increased Ka value. We also discuss the charged double-layer structure, as determined by X-ray crystallographic analysis. Results and Discussion The size-complementary interaction between CPP2
  • -complementary interaction between [5]CPP2+ and [10]CPP. The same size selectivity was observed for the complex formation between neutral CPPs [31]. As the protons in the 1H NMR of [10]CPP2+ and neutral [5]CPP resonate at 4.72 and 7.84 ppm, respectively [21], the observed chemical shifts of the complex indicate
PDF
Album
Supp Info
Letter
Published 23 Feb 2024

Green and sustainable approaches for the Friedel–Crafts reaction between aldehydes and indoles

  • Periklis X. Kolagkis,
  • Eirini M. Galathri and
  • Christoforos G. Kokotos

Beilstein J. Org. Chem. 2024, 20, 379–426, doi:10.3762/bjoc.20.36

Graphical Abstract
  • interesting alternative to hydrogen bonding, which constitute an indispensable type of non-covalent interaction utilized in several catalytic approaches [81][82][83][84][85][86][87][88]. In 2008, Bolm introduced the use of perfluoroiodoalkanes as XB catalysts and the field gained widespread attention as an
PDF
Album
Review
Published 22 Feb 2024

Mechanisms for radical reactions initiating from N-hydroxyphthalimide esters

  • Carlos R. Azpilcueta-Nicolas and
  • Jean-Philip Lumb

Beilstein J. Org. Chem. 2024, 20, 346–378, doi:10.3762/bjoc.20.35

Graphical Abstract
  • ] (Scheme 7A). Cyclic voltammetry measurements of a model NHPI ester showed a shift in its reduction potential from –1.79 V to –1.51 V (vs SCE in MeCN) in the presence of In(OTf)3. As such, it was hypothesized that the Lewis acid lowers the LUMO of the NHPI ester via interaction with the oxygen lone pair in
  • oxidative quenching photocatalytic cycle employing Ir-based photoreductants and a Brønsted acid additive. While the interaction between the RAE 32 and diphenyl phosphoric acid involves hydrogen bonding, in analogy to the Glorius proposal, it is thought that the substrate activation occurs through proton
  • electron reduction of 58, generating the persistent radical 147 and the transient species 148, which fragments into tert-butyl radical (64). Notably, the reduction of NHPI ester 58 could be facilitated by interaction of a cesium cation with the oxygen lone pair of the phthalimide, in analogy to the
PDF
Album
Perspective
Published 21 Feb 2024

Facile approach to N,O,S-heteropentacycles via condensation of sterically crowded 3H-phenoxazin-3-one with ortho-substituted anilines

  • Eugeny Ivakhnenko,
  • Vasily Malay,
  • Pavel Knyazev,
  • Nikita Merezhko,
  • Nadezhda Makarova,
  • Oleg Demidov,
  • Gennady Borodkin,
  • Andrey Starikov and
  • Vladimir Minkin

Beilstein J. Org. Chem. 2024, 20, 336–345, doi:10.3762/bjoc.20.34

Graphical Abstract
  • electrophilic center C(1) of 1 is much lower. It comes, therefore, with no surprise that the interaction of arylamines and the 5-hydroxy and 5-acetoxy derivatives of 3H-phenoxazin-3-one is directed toward the C(2) reaction center to yield 2-amino-3H-phenoxazin-3-ones as the final products under aerobic
PDF
Album
Supp Info
Full Research Paper
Published 21 Feb 2024

Spatial arrangements of cyclodextrin host–guest complexes in solution studied by 13C NMR and molecular modelling

  • Konstantin Lebedinskiy,
  • Ivan Barvík,
  • Zdeněk Tošner,
  • Ivana Císařová,
  • Jindřich Jindřich and
  • Radim Hrdina

Beilstein J. Org. Chem. 2024, 20, 331–335, doi:10.3762/bjoc.20.33

Graphical Abstract
  • spectra indicated the interaction of the guest molecule with the host. In cases where the split of prochiral carbons was observed, 13C NMR spectra showed which pair of prochiral carbons in the guest molecule is close to the wall of the host’s chiral cavity, creating an anisotropic environment. For
PDF
Album
Supp Info
Full Research Paper
Published 20 Feb 2024

Elucidating the glycan-binding specificity and structure of Cucumis melo agglutinin, a new R-type lectin

  • Jon Lundstrøm,
  • Emilie Gillon,
  • Valérie Chazalet,
  • Nicole Kerekes,
  • Antonio Di Maio,
  • Ten Feizi,
  • Yan Liu,
  • Annabelle Varrot and
  • Daniel Bojar

Beilstein J. Org. Chem. 2024, 20, 306–320, doi:10.3762/bjoc.20.31

Graphical Abstract
  • ) spectroscopy to derive binding constants for the interaction between CMA1 and GalNAc. A single cycle kinetics approach was applied, resulting in a measured KD of 1.66 ± 0.08 µM (Figure 3d,e). Inhibiting binding of CMA1 to the GalNAc chip through a dilution series of N-acetyllactosamine (LacNAc) via multicycle
  • interaction with the aromatic ring of Tyr26 (Figure 4c). Further, beyond the C2 position of galactose, a cavity filled with coordinated water molecules hinted at the binding mode for C2-substituted galactose. Notably, the seemingly inactive beta site was found to be occupied by a cadmium ion (Figure S4
  • (CA18132) and INNOGLY (CA18103) COST actions awarded to J.L. This work was further supported by the Protein-Glycan Interaction Resource of the CFG and the National Center for Functional Glycomics (NCFG) at Beth Israel Deaconess Medical Center, Harvard Medical School (supporting grant R24 GM137763). The
PDF
Album
Supp Info
Full Research Paper
Published 19 Feb 2024

Synthesis of π-conjugated polycyclic compounds by late-stage extrusion of chalcogen fragments

  • Aissam Okba,
  • Pablo Simón Marqués,
  • Kyohei Matsuo,
  • Naoki Aratani,
  • Hiroko Yamada,
  • Gwénaël Rapenne and
  • Claire Kammerer

Beilstein J. Org. Chem. 2024, 20, 287–305, doi:10.3762/bjoc.20.30

Graphical Abstract
  • , along with the 5-membered 1,8-naphthalene disulfide 49 resulting from the ring contraction of precursor 47. Such SO transfer process, favoured by the peri-interaction existing in the trisulfide-2-oxide substrate, was also successfully promoted by light and the cyclic sulfoxide 50 was obtained under
PDF
Album
Review
Published 15 Feb 2024

Additive-controlled chemoselective inter-/intramolecular hydroamination via electrochemical PCET process

  • Kazuhiro Okamoto,
  • Naoki Shida and
  • Mahito Atobe

Beilstein J. Org. Chem. 2024, 20, 264–271, doi:10.3762/bjoc.20.27

Graphical Abstract
  • amidyl radical generation through the PCET mechanism. The above studies provided us with valuable insights into the intriguing electrochemical behavior of 1 (Figure 3). Hydrogen bond formation between 1 and the phosphate base yielded small aggregates, the interaction efficiency of which with the
  • radical could access MVK because it still had a large surface area for interaction with the solution interface. As mentioned above, the amidyl radical can also be generated through N−Cl species B. However, the large hydrogen-bond complex, which included HFIP, prevented amidyl radical access to MVK. In
  • was 0.01 M. A glassy carbon anode (φ 3 mm) and Pt cathode (φ 3 mm) were used. Scan rate = 100 mV/s. Plausible models illustrating the size effect of the hydrogen bond complex on the interaction efficiency with electrode surfaces. Plausible mechanism for the inter-/intramolecular hydroamination of 1
PDF
Album
Supp Info
Full Research Paper
Published 12 Feb 2024

Substitution reactions in the acenaphthene analog of quino[7,8-h]quinoline and an unusual synthesis of the corresponding acenaphthylenes by tele-elimination

  • Ekaterina V. Kolupaeva,
  • Narek A. Dzhangiryan,
  • Alexander F. Pozharskii,
  • Oleg P. Demidov and
  • Valery A. Ozeryanskii

Beilstein J. Org. Chem. 2024, 20, 243–253, doi:10.3762/bjoc.20.24

Graphical Abstract
  • unchanged, although quinoline and its derivatives are easily aminated under the same conditions [17]. No interaction occurred under the conditions of the Chichibabin reaction in an attempt to aminate compound 5 with sodium amide in N,N-dimethylaniline at 140–155 °C for an hour. Thus, quinoquinoline 5
  • assumed admixture 11. Mononitration of compound 5. Dehydrogenation of compounds 10 and 11. Nucleophilic methoxylation of compounds 10(12). Electrophilic bromination of compound 5. tele-Elimination upon interaction of dibromide 15 with pyrrolidine. Interaction of dibromide 15 with anionic bases. Comparison
PDF
Album
Supp Info
Full Research Paper
Published 08 Feb 2024

Photochromic derivatives of indigo: historical overview of development, challenges and applications

  • Gökhan Kaplan,
  • Zeynel Seferoğlu and
  • Daria V. Berdnikova

Beilstein J. Org. Chem. 2024, 20, 228–242, doi:10.3762/bjoc.20.23

Graphical Abstract
  • -aryl-N'-alkylindigo photoswitches 22b, 23c and 23d upon addition of Li+ cations. These studies revealed that the presence of the electron-withdrawing groups on the aryl moiety decreased the charge density on the carbonyl groups and weakened the interaction of the Z-isomers with Li+ that accounted for
PDF
Album
Review
Published 07 Feb 2024

Synthesis of the 3’-O-sulfated TF antigen with a TEG-N3 linker for glycodendrimersomes preparation to study lectin binding

  • Mark Reihill,
  • Hanyue Ma,
  • Dennis Bengtsson and
  • Stefan Oscarson

Beilstein J. Org. Chem. 2024, 20, 173–180, doi:10.3762/bjoc.20.17

Graphical Abstract
  • (β-ᴅ-GalNAc-(1→4)-β-ᴅ-GlcNAc), which have then been used for production of the glycodenrimersomes and interaction studies with various galectins [1][2]. In the continuation of this collaboration, to investigate the binding of siglec-1 and the chimera of 3’-SuTF-binding siglecs and TF-binding galectin
  • -3, TEG-N3 glycosides of the TF antigen (β-ᴅ-Gal-(1→3)-α-ᴅ-GalNAc, 1) and its 3’-O-sulfated analogue (2, Figure 1) were required on a gram scale to allow efficient synthesis of the glycodendrisomes. The TF antigen is presented on the surface of most human cancer cell types and its interaction with
  • been developed for further interaction studies with lectins (galectins and siglecs). The synthesis of the 3’-Su-TF antigen 2 comprises eight steps from the known N-galactosamine donor 3, where two of the steps, removal of the Troc- and DTBS protecting groups are performed in the same pot and the
PDF
Album
Supp Info
Full Research Paper
Published 30 Jan 2024

Tandem Hock and Friedel–Crafts reactions allowing an expedient synthesis of a cyclolignan-type scaffold

  • Viktoria A. Ikonnikova,
  • Cristina Cheibas,
  • Oscar Gayraud,
  • Alexandra E. Bosnidou,
  • Nicolas Casaretto,
  • Gilles Frison and
  • Bastien Nay

Beilstein J. Org. Chem. 2024, 20, 162–169, doi:10.3762/bjoc.20.15

Graphical Abstract
  • oxocarbenium 7 and 7’ which exists as a stabilized form including an intramolecular stabilizing interaction between the carbocation and the ester carbonyl group. However, in close agreement with Hess and Baldwin’s values found for the rearrangement of cis-1,3-pentadiene [24], this transition state was high in
PDF
Album
Supp Info
Full Research Paper
Published 25 Jan 2024

Photoinduced in situ generation of DNA-targeting ligands: DNA-binding and DNA-photodamaging properties of benzo[c]quinolizinium ions

  • Julika Schlosser,
  • Olga Fedorova,
  • Yuri Fedorov and
  • Heiko Ihmels

Beilstein J. Org. Chem. 2024, 20, 101–117, doi:10.3762/bjoc.20.11

Graphical Abstract
  • ) in Na phosphate buffer, cNa+ = 16 mM. Blue: spectrum of the starting material before irradiation; red: spectrum at the end of the irradiation. Photoinduced formation of benzo[c]quinolizinium and its interaction with DNA upon intercalation. Synthesis of styrylpyridine derivatives 2a–g. Conditions: i
PDF
Album
Supp Info
Full Research Paper
Published 18 Jan 2024

Electron-beam-promoted fullerene dimerization in nanotubes: insights from DFT computations

  • Laura Abella,
  • Gerard Novell-Leruth,
  • Josep M. Ricart,
  • Josep M. Poblet and
  • Antonio Rodríguez-Fortea

Beilstein J. Org. Chem. 2024, 20, 92–100, doi:10.3762/bjoc.20.10

Graphical Abstract
  • nanotubular-shaped fullerene inside the peapod. Kinetic analysis with the variable-temperature (VT) SMART-TEM method for the aforementioned C60 dimerization has also been reported by these authors [9]. They concluded that the SWCNT, which accumulates energy by the interaction with the electron beam, activates
  • analyzed the interaction between C60 and the nanotube within the peapod. Next, we have found that some dimeric C60–C60 fullerene structures inside the carbon nanotube are thermodynamically favorable. Experiments indicate that, besides C60 sensitization via a singlet excited state, the [2 + 2] cycloaddition
  • the subsequent irreversible C–C fusions occurring in phase 2 are proposed with the help of accelerated Car–Parrinello MD simulations. Results and Discussion Nanotube-C60 interaction: stabilization of the peapod First, we estimated the size of the stabilizing interaction that holds the peapod, that is
PDF
Album
Supp Info
Full Research Paper
Published 17 Jan 2024

Optimizing reaction conditions for the light-driven hydrogen evolution in a loop photoreactor

  • Pengcheng Li,
  • Daniel Kowalczyk,
  • Johannes Liessem,
  • Mohamed M. Elnagar,
  • Dariusz Mitoraj,
  • Radim Beranek and
  • Dirk Ziegenbalg

Beilstein J. Org. Chem. 2024, 20, 74–91, doi:10.3762/bjoc.20.9

Graphical Abstract
  • check if there are any interactions between the studied parameters. After the insignificant parameter interaction terms were removed from the quadratic model, the interaction of photocatalyst loading and stirring speed has a “Prob>F” value of 0.0279, which means this interaction term also significantly
  • affects the maximum hydrogen generation rate. The interaction effect was summarized in the modified quadratic model, which has a difference between R2adj and R2pred of 0.0863. Moreover, an ANOVA showed that the p-value of the linear and modified quadratic model is lower than 0.0001, which confirms that
  • actual experimental hydrogen generation rate could be achieved. No significant difference between the prediction accuracy of the two models is observable. The only difference between the two models is that the modified model considers the interaction of parameters. Therefore, to validate the model from
PDF
Album
Supp Info
Full Research Paper
Published 16 Jan 2024

Preparing a liquid crystalline dispersion of carbon nanotubes with high aspect ratio

  • Keiko Kojima,
  • Nodoka Kosugi,
  • Hirokuni Jintoku,
  • Kazufumi Kobashi and
  • Toshiya Okazaki

Beilstein J. Org. Chem. 2024, 20, 52–58, doi:10.3762/bjoc.20.7

Graphical Abstract
  • beneath the thick bundles form mesh-like structures. The shear force exerted by the bar may not sufficiently align the DWCNTs located near the substrate. Thus, optimizing the interaction between the DWCNTs and substrate is necessary to improve the alignment. To further investigate the low alignment, the
PDF
Album
Supp Info
Full Research Paper
Published 11 Jan 2024

Using the phospha-Michael reaction for making phosphonium phenolate zwitterions

  • Matthias R. Steiner,
  • Max Schmallegger,
  • Larissa Donner,
  • Johann A. Hlina,
  • Christoph Marschner,
  • Judith Baumgartner and
  • Christian Slugovc

Beilstein J. Org. Chem. 2024, 20, 41–51, doi:10.3762/bjoc.20.6

Graphical Abstract
  • O1–C15 and O1–C16 distances are in 2a 3.128(3) and 3.162.3(3) Å and in 2f 3.098(4) and 3.019(4) Å, suggesting a weak hydrogen bonding interaction between O1 and the protons of the methylene groups [43]. The P1–O1 distances of 2.750(1) Å in 2a and 2.693(3) Å in 2f suggest an electrostatic interaction
  • lines) and in methanol (dotted lines); the inset shows a photograph of a vial containing a solution of 2a in chloroform; right: proposed hydrogen bonding interaction in 2b in CHCl3. Conversion of 1 (initial c = 0.25 mM) toward 2a, 2b, or 2d in the presence of the respective Michael acceptors (initial c
PDF
Album
Supp Info
Full Research Paper
Published 10 Jan 2024
Other Beilstein-Institut Open Science Activities